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IRCT201507259014N72 IRCT 2015-08-01 Vice-chancellor for Research the Technology, Hamadan University of Medical Sciences Effect of Zataria Multiflora (Shirazi Thyme) drop versus Nystatine drop on clinical signs and symptoms in patients with denture stomatitis Effect of Zataria Multiflora (Shirazi Thyme) drop versus Nystatine drop on clinical signs and symptoms in patients with denture stomatitis: a triple blind randomized clinical trial 2014-09-23 anticipated 64 Complete https://irct.ir/trial/9511 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Other design features: Randomization: Random assignment of the patients to the intervention and control groups one at a time. Blinding: Patients will be unaware of the type of intervention. The physician who will examine the patients will not be aware of the intervention. The analyzer will be unaware of the type of interventions. Therefore, the trial will be run as triple blind. 2 Denture stomatitis. Intervention 1: Zataria Multiflora (Shirazi Thyme) drop 0.1%, 2.5 ml 4 times a day for 2 weeks. Intervention 2: Nystatine drop 2.5 ml 4 times a day for 2 weeks.
public Dr Zahra Hayati
School of Dentistry, Hamadan University of Medical Sciences, Shahid fahmideh Ave.
Hamadan Iran (Islamic Republic of) +98 81 3838 1086 zah.hayati@gmail.com School of Dentistry scientific Dr Hamid Reza Abdolsamadi
School of Dentistry, Hamadan University of Medical Sciences, Shahid fahmideh Ave.
Hamadan Iran (Islamic Republic of) +98 81 3838 1086 abdolsamadi@umsha.ac.ir School of Dentistry Iran (Islamic Republic of) Inclusion criteria: (a) affected with denture stomatitis type 2 or 3 for at least 11 years; (b) age of 45 to 80 years. Exclusion criteria: (a) sensitivity to Zataria Multiflora or Nystatine; (b) pregnancy; (c) having anemia or malnutrition; (d) having liver disorder, renal diseases, diabetes, xerostomia, hypoparathyroidism, or immunodeficiency; (e) being treated with chemotherapy, antibiotic, or anti-fungal medications. 45 years 80 years Both K12.1 Other forms of stomatitis Treatment - Drugs Treatment - Other Zataria Multiflora (Shirazi Thyme) drop 0.1%, 2.5 ml 4 times a day for 2 weeks Nystatine drop 2.5 ml 4 times a day for 2 weeks Assessing the extent of the inflammation and the number of colonies on palate and mucosal surface of the denture stomatitis. Timepoint: before treatment and 2, 3, 4 weeks after treatment. Method of measurement: through physical examination. Nothing. Timepoint: Nothing. Method of measurement: Nothing. Vice-chancellor for Research the Technology, Hamadan University of Medical Sciences Approved 2015-04-11 Ethic Committee of Hamadan University of Medical Sciences Vice-chancellor for Research the Technology, Hamadan University of Medical Sciences, Shahid Fahmideh Ave Hamadan Iran (Islamic Republic of)