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IRCT20261004071288N1 IRCT 2026-10-28 Islamic Azad University, Arak Branch Comparison of the effects of mindfulness training and cognitive behavioral therapy on work-related rumination, mental fatigue, avoidance of unpleasant experiences, and psychological symptoms in nurses A Comparative Study of the Effects of Mindfulness-Based Stress Reduction (MBSR) and Cognitive Behavioral Therapy (CBT) on Work-Related Rumination, Mental Fatigue, Experiential Avoidance and Psychological Symptoms among Nurses 2026-10-23 anticipated 60 Recruiting https://irct.ir/trial/93832 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Education/Guidance, Randomization description: First, the first intervention group will be coded as A, the second intervention group as B, and the control group as C. Then, a randomization list will be generated using the website www.sealedenvelope.com/simple-randomiser/v1/lists, with a total sample size of 60 participants (three groups of 20 participants each) and a balanced block randomization method with a block size of six. Subsequently, the participants enrolled in the study will be assigned to one of the three groups according to the generated randomization list. For example, suppose the allocation sequence for the first block of six participants is CCABBA. Accordingly, the first and second participants will be assigned to group C, the third and sixth participants to group A, and the fourth and fifth participants to group B. This procedure will continue in the same manner until the final participant (the 60th participant) has been assigned to a group. N/A Condition 1: Work-related rumination. Condition 2: mental fatigue. Condition 3: experiential avoidance. Condition 4: psychological symptoms. Intervention 1: Mindfulness-Based Stress Reduction (MBSR): This intervention is based on the Kabat-Zinn (2013) protocol and consists of eight weekly group sessions, each lasting 90 minutes. Sessions include mindfulness education, practical exercises, group discussions, and home assignments. The content covers body scanning, sitting meditation, breathing awareness, mindful yoga, mindful eating and daily activities, observation and acceptance of thoughts and emotions, stress and anger management, interpersonal relationship improvement, and emotion regulation. At the end of the program, strategies for maintaining regular practice and setting short-term and long-term goals are introduced. Intervention 2: Cognitive Behavioral Therapy (CBT): This intervention is based on the therapeutic framework of Wildermuth (2008) and consists of nine weekly group sessions, each lasting 60–90 minutes. The sessions cover group orientation, relaxation and stress management, identification and recording of automatic thoughts, identification and modification of dysfunctional thoughts and beliefs, cognitive restructuring, problem-solving and assertiveness training, activity scheduling, review of learned skills, and relapse prevention. Intervention 3: Control group: They will not receive any structured psychological intervention as part of the study and will only participate in the research assessments. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No further information is available
public Zahra Sakeni
Shahed Street, Shahid Najafzadeh Alley
Kashan Iran (Islamic Republic of) 8714793177 +98 31 5527 7126 sakeni-z@kaums.ac.ir Kashan University of Medical Sciences scientific Zahra Zanjani
Kashan University of Medical Sciences, Pezeshk Blvd., Ghotbe Ravandi Blvd., Kashan, Iran
Kashan Iran (Islamic Republic of) 8715988141 +98 31 5558 9399 zanjani-z@kaums.ac.ir Kashan University of Medical Sciences Iran (Islamic Republic of) Holding at least a bachelor's degree in Nursing. Being between 22 and 50 years of age. Being employed at a hospital. Scoring above 8 on the anxiety subscale or above 13 on the depression subscale of the DASS-21 questionnaire. 22 years 50 years Both Having acute or chronic physical disorders, including cancer and multiple sclerosis (MS) Having any hearing, speech, or visual impairment Concurrent participation in another educational program F00–F99 F00–F99 F00–F99 F00–F99 Mental and behavioural disorders Mental and behavioural disorders Mental and behavioural disorders Mental and behavioural disorders Behavior Behavior N/A Mindfulness-Based Stress Reduction (MBSR): This intervention is based on the Kabat-Zinn (2013) protocol and consists of eight weekly group sessions, each lasting 90 minutes. Sessions include mindfulness education, practical exercises, group discussions, and home assignments. The content covers body scanning, sitting meditation, breathing awareness, mindful yoga, mindful eating and daily activities, observation and acceptance of thoughts and emotions, stress and anger management, interpersonal relationship improvement, and emotion regulation. At the end of the program, strategies for maintaining regular practice and setting short-term and long-term goals are introduced. Cognitive Behavioral Therapy (CBT): This intervention is based on the therapeutic framework of Wildermuth (2008) and consists of nine weekly group sessions, each lasting 60–90 minutes. The sessions cover group orientation, relaxation and stress management, identification and recording of automatic thoughts, identification and modification of dysfunctional thoughts and beliefs, cognitive restructuring, problem-solving and assertiveness training, activity scheduling, review of learned skills, and relapse prevention. Control group: They will not receive any structured psychological intervention as part of the study and will only participate in the research assessments. Work-related rumination. Timepoint: Before the start of the study and immediately after the final intervention session. Method of measurement: 15-item Work-Related Rumination Questionnaire (WRRQ). Mental fatigue. Timepoint: Before the start of the study and immediately after the final intervention session. Method of measurement: 20-item Multidimensional Fatigue Inventory (MFI). Experiential avoidance. Timepoint: Before the start of the study and immediately after the final intervention session. Method of measurement: 10-item Acceptance and Action Questionnaire–II (AAQ-II). Psychological symptoms. Timepoint: Before the start of the study and immediately after the final intervention session. Method of measurement: 21-item Depression, Anxiety and Stress Scale (DASS-21). Islamic Azad University, Arak Branch Approved 2026-09-27 Research Ethics Committees of Islamic Azad University- Arak Branch Amirkabir University Campus, 3rd km of Khomein Road, Imam Khomeini Blvd., Imam Khomeini Sq., Arak, Iran Arak Markazi Iran (Islamic Republic of)