]>
IRCT201201308878N1 IRCT 2012-05-05 Tabriz University Of Medical Sciences Magnesium Sulfate In Adverse With Nifedipine In suppression preterm labor In Pregnant With Preterm Labor Magnesium Sulfate In Adverse With Nifedipine In Suppression Preterm labor In Pregnant With Preterm Labor 2012-04-20 anticipated 80 Complete https://irct.ir/trial/9362 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. N/A Preterm labor. Intervention 1: First group (A) will be giving 4 gram Magnesium Sulfate as a loading dose then countining 2 gram every hour until 48 hours(positive Patella reflex ,at least 12 times respiratory rates,urine output at least 30mm)at the same time this group will be giving Placebo tablet instead of Nifedipine. Intervention 2: The other group will be giving Nifedipine tablet(20mg) after half an hour will be given other 20 mg of Nifedipine tablet,if contractions persist ,giving 20 mg Nifedipin will be countining every 3-8 hours until contractions will subside.at the same time serum Ringer with microset will be conduct as Plasebo.
public Fereshteh Fartash
Sought Shariaty Street
Tabriz Iran (Islamic Republic of) 5138851559 +98 41 1666 1428 fereshtefartash@gmail.comfereshtehfartash@yahoo.com Nursing and Midwifery University of Tabriz scientific Fahimeh Sehhatieh Shafaee
Sought Shariaty Street
Tabriz Iran (Islamic Republic of) 5138856913 +98 41 1477 7379 Fahimehsehhatie@yahoo.comsehhatief@tbzmed.ac.ir Nursing And Midwifery Of Tabriz University Iran (Islamic Republic of) Iran (Islamic Republic of) Criteria include more than 6 contractions per hour resulting in a demonstrated cervical change or presumed prior cervical change (transvaginal cervical length < 2.5 cm, >50% cervical effacement, or cervical dilation ≥2 cm) ;Gestational ages are between 26-34 ; Bloody show ; Nully fetus pregnant ; Intact membranes ; BP>90 mmhg in Nifedipine group exclude criteria Oligohydramnios and polyhydramnios ;Nonreactive nonstress test results ;Positive contraction stress test results ; Absent or reversed diastolic flow upon Doppler examination of umbilical blood flow ; Repetitive severe variable decelerations ;Significant vaginal bleeding consistent with abruption and placenta previa ; PPROM ;Multi fetus pregnancy ;BP<90 mmhg in Nifedipine group ; Intrauterine infection ; Pyelonefrites ;Preeclampse and GTM and anomalies 14 years 45 years Female O60.0 Preterm labour without delivery Treatment - Drugs Treatment - Drugs First group (A) will be giving 4 gram Magnesium Sulfate as a loading dose then countining 2 gram every hour until 48 hours(positive Patella reflex ,at least 12 times respiratory rates,urine output at least 30mm)at the same time this group will be giving Placebo tablet instead of Nifedipine The other group will be giving Nifedipine tablet(20mg) after half an hour will be given other 20 mg of Nifedipine tablet,if contractions persist ,giving 20 mg Nifedipin will be countining every 3-8 hours until contractions will subside.at the same time serum Ringer with microset will be conduct as Plasebo Effecement. Timepoint: In addmission. Method of measurement: Vaginal examination. Dillatation. Timepoint: In admmision. Method of measurement: Vaginal examination. Length and diuration of contractions. Timepoint: Every 10 minute. Method of measurement: Abdominal tough of uterus. Feeling of fetal movment by mother. Timepoint: In an hour. Method of measurement: Abdominal touching. Unreliable paterns of fetal heart rate. Timepoint: In 20 minnutes. Method of measurement: Record by monitoring devices. Newborn Apgar. Timepoint: In first and fifth min. Method of measurement: Apgars score. ABG of umblical cord blood. Timepoint: After birth. Method of measurement: ABG devices. Meconium. Timepoint: After birth. Method of measurement: Finding meconium on neuborn skin or amniotic fluid or amblical cord. Tabriz University Of Medical Sciences Approved 2011-11-21 Medical Science Of Tabriz University Tabriz, Golgasht St. Tabriz Iran (Islamic Republic of)