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IRCT20260714070191N1 IRCT 2026-07-27 National Science Foundation of Iran (INSF) Effects of Exercise on Cognitive Factors in Elderly Women with Diabetes A Comparison of the Effects of Eight Weeks of Combined Exercise Training with Two Different Intensities on Attentional Networks, Blood-Brain Barrier-Related Factors, and Explicit Motor Memory in Older Women with Type 2 DiabetesResearch ethics committi of Lourestan univercity 2026-09-02 anticipated 60 Complete https://irct.ir/trial/91715 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Crossover, Purpose: Basic scienece, Randomization description: Simple Randomization, Blinding description: Due to the nature of the exercise intervention, blinding of participants and exercise trainers is not feasible. However, outcome assessors (responsible for cognitive, laboratory, and functional measurements) and data analysts will be blinded to participants’ group allocation. The group assignment information will be maintained by the principal investigator. N/A Condition 1: Diabetes. Condition 2: Diabetes. Intervention 1: Hypertrophy Resistance Training Group. Intervention 2: Intervention group: Endurance Resistance Training Group. No - There is not a plan to make this available Justification or reason for not sharing IPD is no more information
public Zahra Hemati
No. 1, Alley 4, North Farabi Street, Shahrekord, Iran
Shahrekord Iran (Islamic Republic of) 8815716891 0989137728628 zhemati@ardakan.ac.ir دانشگاه اردکان scientific Zahra Hemati
No. 1, Alley 4, North Farabi Street
Shahrekord Iran (Islamic Republic of) 8815716891 +98 913 772 8628 zhemati@ardakan.ac.ir University of Ardakan Iran (Islamic Republic of) Participants must have a physician-confirmed diagnosis of type 2 diabetes mellitus, HbA1c ≥ 6.5%, fasting blood glucose (FBG) ≥ 126 mg/dL (7.0 mmol/L), and be receiving oral antidiabetic medication. 60 years 70 years Female E10.4 E10.4 Type 1 diabetes mellitus with neurological complications Type 1 diabetes mellitus with neurological complications Treatment - Other Treatment - Other Hypertrophy Resistance Training Group Intervention group: Endurance Resistance Training Group AQP4 (Aquaporin-4). Timepoint: Study Start and End Dates. Method of measurement: Using specialized laboratory kits. Calpain. Timepoint: Study Start and End Dates. Method of measurement: kit. GFAP. Timepoint: Study Start and End Dates. Method of measurement: kits. S100B. Timepoint: Study Start and End Dates. Method of measurement: kit. National Science Foundation of Iran (INSF) Approved 2025-11-19 Lorestan University Research Ethics Committee Golshan 2 Street Khorramabad Lorestan Iran (Islamic Republic of)