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IRCT201201178656N1 IRCT 2012-01-21 Isfahan University of Medical Sciences Efficacy of IPL in acne Efficacy of intense pulsed light combined with topical erythromycin solution 2% versus topical erythromycin solution 2% alone in the treatment of persistent facial erythematous acne macules 2010-01-01 anticipated 35 Complete https://irct.ir/trial/9147 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A Acne vulgaris. Intervention 1: Intetrvention group is right side of face. we done 3 IPL sessions with 2 weeks interval and also advised the patients to apply topical erythromycin lotion 2% twice daily from start of the study until 3 months after the third IPL session. the setting of IPL was: 530-1100nm wavelength, one pass, fluence of 14-16 J/cm2, and program of 14-18. Intervention 2: Control group was left side of face that was only treated by topical erythromycin lotion2% twice daily.
public Dr Amin Kharaziha Isfahani
Isfahan University of Medical SciencesHazar jarib ave.
Isfahan Iran (Islamic Republic of) +98 31 1792 2406 kharazi@resident.mui.ac.ir Isfahan University of Medical Sciences scientific Dr Gita Faghihi
Isfahan University of Medical Sciences
Isfahan Iran (Islamic Republic of) +98 31 1792 2406 faghihi_g@med.mui.ac.ir Isfahan University of Medical Sciences Iran (Islamic Republic of) In our study inclusion criterions were the presence of at least 5 persistent erythematous macules on every side of the patients' face and these macules should be complication of inflammatory acne lesions and these macules should be persistent even with receiving at least two months of standard treatments. Exclusion criterions were oral retinoid use from 6 months before the study, necessity of systemic treatments (i.e. nodulocystic or scarring acne), history of keloid, vitiligo, drugs that exacerbate or remit acne lesions, history of skin cancer, photosensitivity disorders and history of poor wound healing such as diabetes mellitus no limit no limit Both L70.0 Acne vulgaris Treatment - Devices Treatment - Drugs Intetrvention group is right side of face. we done 3 IPL sessions with 2 weeks interval and also advised the patients to apply topical erythromycin lotion 2% twice daily from start of the study until 3 months after the third IPL session. the setting of IPL was: 530-1100nm wavelength, one pass, fluence of 14-16 J/cm2, and program of 14-18. Control group was left side of face that was only treated by topical erythromycin lotion2% twice daily. Persistent erythematous macules of facial acne. Timepoint: Before the study, before every IPL session, 1 and 3 months after last IPL session. Method of measurement: Counting and photography. Erythema. Timepoint: One week after every IPL session. Method of measurement: Questionnaire. Pain. Timepoint: One week after every IPL session. Method of measurement: Questionnaire. Photosensitivity. Timepoint: One week after every IPL session. Method of measurement: Questionnaire. Swelling. Timepoint: One week after every IPL session. Method of measurement: Questionnaire. Blister. Timepoint: One week after every IPL session. Method of measurement: Questionnaire. Crusting. Timepoint: One week after every IPL session. Method of measurement: Questionnaire. Isfahan University of Medical Sciences Approved 2010-03-14 Isfahan University of Medical Sciences Ethics Committee Isfahan University of Medical Sciences Isfahan Iran (Islamic Republic of)