<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20251110067946N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2026-06-03</date_registration>
      <primary_sponsor>Vice President for Research, Shahid Beheshti University</primary_sponsor>
      <public_title>Comparison of Two Types of Exercise Training on Balance, Motor Performance, Trunk Control, and Quality of Life in Patients with Parkinson’s Disease</public_title>
      <acronym>TOCT-DNS-PD</acronym>
      <scientific_title>Comparing the effects of task-oriented circuit training (TOCT) and dynamic neuromuscular stabilization training (DNS) on balance, motor function, trunk control, and quality of life in people with Parkinson's disease: A randomized clinical trial</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2026-05-11</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>30</target_size>
      <recruitment_status>Recruiting</recruitment_status>
      <url>https://irct.ir/trial/88426</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: Participants who met the inclusion criteria were randomly assigned to one of three groups: TOCT, DNS, or control. Randomization was performed using a simple allocation method, with individual participants as the unit of randomization. To maintain allocation concealment, sealed and coded paper envelopes were used. Each envelope contained the group assignment and was opened sequentially according to the order of participant enrollment to prevent prior allocation.</study_design>
      <phase>N/A</phase>
      <hc_freetext>Parkinson.</hc_freetext>
      <i_freetext>Intervention 1: the first intervention group : dynamic neuromuscular stabilization exercises 3 times per week for 6 weeks , each training session consisted of three main parts : warm - up for 5 min , dynamic muscle - dynamic stabilization for 50 min and chilling for 5 min . sets of rest intervals between sets are between 60 and 150 seconds . the exercises consist of various motor patterns performed in different situations and exercises with the control of breathing are performed . Intervention 2: the second intervention group : وظیفه‌محوربیماران - based training program : parkinson " s disease , 3 sessions per week for 6 weeks before starting the training program , 5 min before the start of training program , and in the last 50 minutes , they had their سردکردن in their training program . these include repeating tasks , in order to achieve and maintain the motor learning of these tasks . Intervention 3: Control group: receive no intervention and continue to live in normal life.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Undecided - It is not yet known if there will be a plan to make this available</results_IPD_plan>
      <results_IPD_description>Justification or reason for indecision in sharing IPD is There is no further information</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Marziyeh ardeshiri lordejani</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Shahid Beheshti University, Shahid Shahryari Square, Evin, Tehran</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>1983969411</zip>
        <telephone>+98 913 464 9084</telephone>
        <email>ardeshirineda3@gmail.com</email>
        <affiliation>The university of shahid beheshti</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Amir Hossein Barati</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Shahid Beheshti University, Shahid Shahryari Square, Evin, Tehran</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>1983969411</zip>
        <telephone>+98 21 29901</telephone>
        <email>ahbarati20@gmail.com</email>
        <affiliation>Shahid Beheshti University Faculty of Sports and Health Sciences</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>Diagnosis of Parkinson’s disease based on official clinical diagnostic criteria, accompanied by gait impairment.
Age range: 55 to 75 years.
Hoehn and Yahr stage III of Parkinson’s disease.
Independence from assistive devices, with the ability to walk without using a cane or walker.
Absence of stroke, peripheral neuropathy, and other serious diseases that could affect the study outcomes.
Normal body mass index (BMI) ranging from 18.5 to 25.
Completion of the informed consent form and willingness to participate in the study.</inclusion_criteria>
      <agemin>55 years</agemin>
      <agemax>75 years</agemax>
      <gender>Both</gender>
      <exclusion_criteria>Absence from more than three sessions of the scheduled training program.
Withdrawal of consent or unwillingness to continue participation in the study.
Exacerbation of Parkinson’s disease symptoms.</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>G20</hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword>Parkinson's disease</hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Rehabilitation</i_code>
      <i_code>Rehabilitation</i_code>
      <i_code>N/A</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>the first intervention group : dynamic neuromuscular stabilization exercises 3 times per week for 6 weeks , each training session consisted of three main parts : warm - up for 5 min , dynamic muscle - dynamic stabilization for 50 min and chilling for 5 min . sets of rest intervals between sets are between 60 and 150 seconds . the exercises consist of various motor patterns performed in different situations and exercises with the control of breathing are performed .</i_keyword>
      <i_keyword>the second intervention group : وظیفه‌محوربیماران - based training program : parkinson " s disease , 3 sessions per week for 6 weeks before starting the training program , 5 min before the start of training program , and in the last 50 minutes , they had their سردکردن in their training program . these include repeating tasks , in order to achieve and maintain the motor learning of these tasks .</i_keyword>
      <i_keyword>Control group: receive no intervention and continue to live in normal life.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Balance. Timepoint: Balance will be assessed at baseline (prior to the intervention) and again following the completion of a six-week training program. Method of measurement: Mini-Balance Evaluation Systems Test.</prim_outcome>
      <prim_outcome>Motor Function. Timepoint: Motor Function will be assessed at baseline (prior to the intervention) and again following the completion of a six-week training program. Method of measurement: Timed Up and Go (TUG).</prim_outcome>
      <prim_outcome>Trunk Control. Timepoint: Trunk Control will be assessed at baseline (prior to the intervention) and again following the completion of a six-week training program. Method of measurement: Trunk Impairment Scale (TIS).</prim_outcome>
      <prim_outcome>Quality of Life. Timepoint: Quality of Life will be assessed at baseline (prior to the intervention) and again following the completion of a six-week training program. Method of measurement: Quality of Life questionnaire (PDQ-39).</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome></sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Vice President for Research, Shahid Beheshti University</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2025-09-06</approval_date>
        <contact_name>Research Ethics Committee, Shahid Beheshti University</contact_name>
        <contact_address>Office of the Vice-Chancellor for Research, Shahid Beheshti University, Ovin Square, Tehran, Iran Tehran Tehran Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
