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IRCT20130812014333N267 IRCT 2025-09-30 Kermanshah University of Medical Sciences Comparative study of two treatment of liver hydatid cyst Comparative study of the results of Simple and Modified PAIR methods in the treatment of liver hydatid cyst 2025-10-12 anticipated 24 Recruiting https://irct.ir/trial/86347 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Simple random method. 24 cards are selected and numbers from 1-24 are inserted on the cards. The cards are placed in an envelope. Two of the design partners take one card out of the envelope each time and announce the card number. Paired numbers are assigned to the intervention group and odd numbers to the control group. N/A Liver Hydatid Cysts. Intervention 1: In the first intervention group (Simple PAIR method), an 18-gauge Shiba needle is inserted into the cyst under ultrasound guidance, and a portion of the cyst contents is evacuated with volume control and then aspirated. The entire cyst contents are aspirated and the cyst is filled with a mixture of nonionic contrast agent and saline solution (½ contrast agent + ½ saline solution 0.09% [NaCl]) equal to the aspirated volume. The cyst cavity contents are aspirated again after the cystogram, and then absolute alcohol (97% ethyl alcohol Merck) is injected in a volume equal to 30% of the aspirated volume. Intervention 2: In the second intervention group (Modified PAIR method), the cyst is punctured with an 18-gauge Shiba needle and a hydrophilic wire is inserted into it. Then, the dissected route is inserted and fixed inside the cyst using a thin 6f dilator and the thinnest available 8f catheter using the Seldinger method. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no further information
public Leila Arghand
Emam Reza Hospital, Parastar Boulevard
Kermanshah Iran (Islamic Republic of) 6715847141 +98 83 3427 6306 Leiliarghand71@gmail.com Kermanshah University of Medical Sciences scientific Dr. Mohammad Gharib Salehi
Emam Reza Hospital, Parastar Boulevard
Keranshah Iran (Islamic Republic of) 6715847141 +98 83 3427 6306 Kumssalehi@yahoo.com Kermanshah University of Medical Sciences Iran (Islamic Republic of) Informed consent People diagnosed with hepatic hydatid cysts no limit no limit Both Patients who are simultaneously infected with pulmonary hydatid cysts B67.0 Echinococcus granulosus infection of liver Treatment - Other Treatment - Other In the first intervention group (Simple PAIR method), an 18-gauge Shiba needle is inserted into the cyst under ultrasound guidance, and a portion of the cyst contents is evacuated with volume control and then aspirated. The entire cyst contents are aspirated and the cyst is filled with a mixture of nonionic contrast agent and saline solution (½ contrast agent + ½ saline solution 0.09% [NaCl]) equal to the aspirated volume. The cyst cavity contents are aspirated again after the cystogram, and then absolute alcohol (97% ethyl alcohol Merck) is injected in a volume equal to 30% of the aspirated volume. In the second intervention group (Modified PAIR method), the cyst is punctured with an 18-gauge Shiba needle and a hydrophilic wire is inserted into it. Then, the dissected route is inserted and fixed inside the cyst using a thin 6f dilator and the thinnest available 8f catheter using the Seldinger method. Hydatid cyst size. Timepoint: First month, third and sixth months, and first year. Method of measurement: Using ultrasound. Hydatid cyst volume. Timepoint: First month, third and sixth months, and first year. Method of measurement: Using ultrasound. Kermanshah University of Medical Sciences Approved 2025-04-27 Kermanshah University of Medical Sciences, Ethics Committee of the Faculty of Medicine Vice Chancellor for Research Affairs, Kermanshah University of Medical Sciences, Building No.2, Shahid Beheshti Boulevard Kermanshah Kermanshah Iran (Islamic Republic of)