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IRCT20250714066483N1 IRCT 2025-10-30 Hamedan University of Medical Sciences Investigating the Influence of Dry Eye Disease and Artificial Tear eye drop on the Biometry Repeatability and Accuracy in Patients with Cataract Investigating the Influence of Dry Eye Disease and Artificial Tear eye drop on the Biometry Repeatability and Accuracy in Patients with Cataract 2024-12-21 anticipated 20 Complete https://irct.ir/trial/86139 interventional Randomization: Not randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention. N/A Condition 1: cataract. Condition 2: Dry eye disease. Intervention 1: Intervention group: primary biometry using IOLMaster-500 and then Instilling tearlose (Sinadaro) artificial tear drop 10 minutes before second biometry in one of a patient's eyes and one month after cataract surgery, measuring refraction and SE using auto refractometer. Intervention 2: Control group: primary biometry using IOLMaster-500 and then not instilling Tearlose (Sinadaro) artificial tear drop 10 minutes before second biometry in one of a patient's eyes and one month after cataract surgery, measuring refraction and SE using auto refractometer. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Due to the incompleteness and the uncertainty of the significance of the result of the project, I have not yet decided to whether publish the various parts of the project or not.
public Elham Soltani
Mirzadeh Eshghi street , Farshchian (Sina) Hospital
Hamadan Iran (Islamic Republic of) 6516848741 +98 81 3826 5706 e.soltani@umsha.ac.ir Hamedan University of Medical Sciences scientific Elham Soltani
Mirzadeh Eshghi street , Farshchian (Sina) Hospital
Hamadan Iran (Islamic Republic of) 6516848741 +98 81 3826 5706 e.soltani@umsha.ac.ir Hamedan University of Medical Sciences Iran (Islamic Republic of) Patients aged 50 to 70 years with bilateral cataract and mild to moderate Dry eye disease Informed consent to participate in the study Absence of pathologies influencing biometry such as keratoconus, corneal scar, pathologic myopia, nanophthalmus, etc Absence of prior ocular surgical history 50 years 70 years Both Any intra- or postoperative complication occurance Patient's failure to attend follow-up visit H26 H04.12 Other cataract Dry eye syndrome Prevention Prevention Intervention group: primary biometry using IOLMaster-500 and then Instilling tearlose (Sinadaro) artificial tear drop 10 minutes before second biometry in one of a patient's eyes and one month after cataract surgery, measuring refraction and SE using auto refractometer Control group: primary biometry using IOLMaster-500 and then not instilling Tearlose (Sinadaro) artificial tear drop 10 minutes before second biometry in one of a patient's eyes and one month after cataract surgery, measuring refraction and SE using auto refractometer Spherical equivalent. Timepoint: At the beginning of the study and one month after surgery. Method of measurement: Topcon RM8000 autorefractometer. Anterior chamber depth. Timepoint: At the beginning of the study and one month after surgery. Method of measurement: IOL Master 500. Axial length. Timepoint: At the beginning of the study and one month after surgery. Method of measurement: IOL Master 500. Mean keratometry. Timepoint: At the beginning of the study and one month after surgery. Method of measurement: Topcon RM8000 autorefractometer. Corneal astigmatism. Timepoint: At the beginning of the study and one month after surgery. Method of measurement: Topcon RM8000 autorefractometer. Dry eye disease severity. Timepoint: before intervention. Method of measurement: Schirmer test, TBUT test, and corneal staining. Hamedan University of Medical Sciences Approved 2025-02-16 Ethics committee of Hamedan university of medical sciences Hamedan University of Medical Sciences, Shahid Fahmid Blvd., Pajouhesh Square Hamedan Hamadan Iran (Islamic Republic of)