IRCT20190610043858N1 IRCT 2026-04-20 Iran University of Medical Sciences The effect of Methylprednisolone and Betamethasone on the treatment of lateral epicondylitis The effect of Methylprednisolone and Betamethasone on the treatment of lateral epicondylitis in patients referred to Shafaihiaian and Rasoul Akram hospitals in Tehran in 2025;A randomized clinical trial study 2025-07-15 anticipated 36 Complete https://irct.ir/trial/85148 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Eligible patients are distributed into study groups based on pain intensity and age. Specifically, individuals are categorized by age into two groups: ≤ 40 years and > 40 years. Regarding pain intensity, based on the VAS scale, individuals are categorized into two blocks: ≤ 7 and > 7. They are then sequentially and consecutively assigned to study groups A and B. Individuals aged ≤ 40 years are classified into the above pain intensity categories (Block A and Block B), while individuals aged > 40 years are classified into the same pain intensity categories (Block C and Block D). These categories are labeled with the corresponding Persian letters in the checklist, so the distribution of patients across groups is symbolically represented to maintain consistency, Blinding description: In this study, participants are unaware of the type of injectable medication being used. Additionally, a trained orthopedic resident who collects data before and after the intervention is also unaware of the type of intervention being performed. 2 Lateral epicondylitis. Intervention 1: Intervention group: A- Local injection of Methylprednisolone (40 mg/mL – Iran Hormone Company) administered at the tendinoperiosteal site approximately 2 cm inferior and anterior to the lateral epicondyle, aligned with the point of maximum tenderness. Intervention 2: Intervention group: Local injection of Betamethasone (4 mg/mL – Aburaihan Company) administered at the tendinoperiosteal site approximately 2 cm inferior and anterior to the lateral epicondyle, aligned with the point of maximum tenderness. No - There is not a plan to make this available Justification or reason for not sharing IPD is Maintaining research ethics