IRCT201410137984N19 IRCT 2014-12-26 Vice chancellor for research, Iran University of Medical Sciences The effect of adding magnesium to bupivacaine for femoral nerve block on postoperative pain in patients undergoing knee and femoral orthopedic operations The effect of adding magnesium to bupivacaine for femoral nerve block on postoperative pain in patients undergoing knee and femoral orthopedic operations 2013-12-22 anticipated 60 Complete https://irct.ir/trial/8433 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. 2-3 Condition 1: Postoperative Analgesia. Condition 2: Postoperative Analgesia. Intervention 1: After the written informed consent from the patients in the study the femoral block perform with guide of sonography and nerve stimulator on the lateral side of femoral artery below the inguinal ligament for confirming the nerve location. In first group30 patient with femur or knee surgery by spinal anesthesia 19.6cc bupivacaine 0.2% with 0.4cc magnesium sulfate 50%(200 mg)perform injection. According to the questionnaire in all of patients the major variables such as VAS ,sedation score,bromage score before block and just after block and in times 3-6-12 after that the same criteria with the consumption of any other analgesic and patient satisfication will evaluate and record. For patients in this study questionnaire fille out by someone who does not know the nature of the injected drugs. Intervention 2: After the written informed consent from the patients in the study the femoral block perform with guide of sonography and nerve stimulator on the lateral side of femoral artery below the inguinal ligament for confirming the nerve location. In second group30 patient with femur or knee surgery by spinal anesthesia with 20cc bupivacaine 0.2% perform injection. According to the questionnaire in all of patients the major variables such as VAS ,sedation score,bromage score before block and just after block and in times 3-6-12 after that the same criteria with the consumption of any other analgesic and patient satisfication will evaluate and record. For patients in this study questionnaire fille out by someone who does not know the nature of the injected drugs.