IRCT20250317065107N1 IRCT 2025-05-11 Mashhad University of Medical Sciences Assessment the effect of trehalose in patients with Lewy body dementia To assess the effect of trehalose on cognitive abillity in patients with Lewy body dementia and evaluation of key proteins in the protein interaction network of LBD 2025-05-22 anticipated 60 Complete https://irct.ir/trial/82764 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Individuals are randomly assigned to two groups: intervention and control using randomized blocks of 2 and 4 (using sealedenvelope.com). After randomization, the type of treatment is written in A/B codes in separate papers and placed in an opaque envelope or the paper will wrap so that no one can see inside the paper (random concealment). After obtaining informed consent from the participants, one paper will be taken in order and according to the noted code, the patient is place in one of the intervention or placebo groups, Blinding description: As mentioned before, after randomization, the patients place in groups of A/B and received the products similar in shape and color (blinding of participants). The information of the patients and theirs treatment groups will be written with randomized codes (A/B) on datasheets (the blinding of the assessor). Data will be entered to the SPSS software with codes (the blinding of the analyzer). 2 Lewy body dementia. Intervention 1: Intervention group: Trehalose (Shanxxi Fruiterco Co. Ltd. China) will be administered orally at a dose of 20 grams per day for up to three months. Intervention 2: Control group: Placebo (sucrose) will be administered 20 grams orally per day for three months. No - There is not a plan to make this available Justification or reason for not sharing IPD is No further information available.