IRCT20241125063843N1 IRCT 2025-01-08 Arak University of Medical Sciences Investigating the effect of oral melatonin on urinary tract infection in children and adolescents Investigating the effect of oral melatonin on urinary tract infection in children and adolescents 2024-11-26 anticipated 100 Complete https://irct.ir/trial/80392 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Block randomization is done by a statistician with blocks of 6 along with the randomization code through the site sealedenvelope.com, Blinding description: To conduct this double-blind study, before starting the investigation, the total number of capsules for both the intervention and control groups, which are identical in shape, color, and appearance and obtained from the same pharmaceutical company, will be coded as A and B by a person other than the researcher to ensure that the researcher remains unaware of which type of capsules each group receives. Additionally, the participants, who are randomly assigned to groups A and B without knowledge of whether they are in the supplement or placebo group, will receive the capsules for a duration of 10 days. 3 Urinary tract infection. Intervention 1: Intervention group:In addition to receiving standard antibiotic treatment, patients will receive 5 mg melatonin tablets produced by Jalinous Iranian Pharmaceutical Company at a dose of 5 mg once a day for 10 days. Intervention 2: Control Group: Patients will receive standard antibiotic treatment for urinary tract infection for 10 days, along with a placebo of 5 mg melatonin tablets produced by the Iranian pharmaceutical company Jalinos, which has a similar appearance to the active drug, taking one tablet daily. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information.