IRCT20240821062823N1 IRCT 2024-09-05 Yazd University of Medical Sciences Effect of TauroLock in prevention of catheter-related infection Evaluation of the efficacy or inefficacy of TauroLock in the prevention of catheter-related infection and thrombosis in hemodialysis patients 2024-08-26 anticipated 60 Complete https://irct.ir/trial/78628 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Randomization description: At the time of entering the study, patients are randomized into one of the two intervention groups using a table of random numbers, Blinding description: In this study, the participants and the main researcher and the outcome assessor are unaware of the allocation of the study groups and performing direct therapeutic interventions based on the study design method is the responsibility of the clinical caregivers of the health center. 4 Condition 1: Catheter-related infection. Condition 2: Central venous catheter line thrombosis. Intervention 1: Intervention group: At the end of each dialysis session during a month, the patient's CVC lines are flushed with Taurolock-hep500, and at any time during the study, in case of signs of infection, a blood culture is prepared from the patient's peripheral blood and catheter. Intervention 2: Intervention group: At the end of each dialysis session during a month, the patient's CVC lines are flushed with unfractionated Heparin 5000 i.u/ml , and at any time during the study, in case of signs of infection, a blood culture is prepared from the patient's peripheral blood and catheter. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information