IRCT20240803062624N1 IRCT 2024-10-03 Yasouj University of Medical Sciences "Effect of metronidazol in treatment of hpylori""Effect of levofloxacin in treatment of hpylori" Comparative study of the effect of levofloxacin with metronidazole in the 4-drug eradication regimen of Helicobacter pylori 2023-08-23 anticipated 334 Complete https://irct.ir/trial/78347 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: First, we put the number of participants (167 A cards and 167 B cards) in a dark box, then the selection is made by randomly drawing a card from the box. 2 Helicobacter pylori infection. Intervention 1: Intervention group A: In this group, omeprazole 20 mg twice a day (bid) for two weeks along with an antibiotic regimen (amoxicillin 1 gram twice a day (56 tablets during the treatment period) and two bismuth citrate tablets twice daily and levofloxacin 500 mg daily) and then continue to take omeprazole for 6 weeks without antibiotics and alone, and after this 6-week period, the patient 4 weeks later without taking drugs and antibiotics for the root test Kenny refers to the stool antigen test method.The drugs used in the study are from the pharmaceutical companies of Farabi and Obeidi. Intervention 2: Intervention group B: In this group, omeprazole 20 mg twice a day along with antibiotic regimen (amoxicillin 1 gram twice a day and two bismuth citrate tablets twice a day and metronidazole 500 mg twice a day) were given for two weeks. and then continue taking omeprazole for 6 weeks without antibiotics and alone, and after this 6-week period, the patient will refer to stole antigen test method 4 weeks later without taking drugs and antibiotics.The drugs used in the study are from the pharmaceutical companies of Farabi and Obeidi. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is "There is no further information".