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IRCT20191117045462N18 IRCT 2024-07-23 Riphah International University Effects of resistance training on inflammatory markers, cardiorespiratory fitness and pulmonary functions in patients with Rheumatoid arthritis. Effects of resistance training on inflammatory markers, cardiorespiratory fitness and pulmonary functions in patients with Rheumatoid arthritis. 2024-08-15 anticipated 70 Complete https://irct.ir/trial/78024 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Taking into account the above mentioned inclusion and exclusion criteria, patients will be recruited in the study through convenient sampling technique and then will be randomly assigned to each group through Random Sampling sealed opaque enveloped, Blinding description: Investigator will be blind. Assesmnt will be done by 2nd therapist who will not be involved in treatment and data analysis. N/A Patients with rheumatoid arthritis. Intervention 1: Intervention group: Resistance exercise training: Patients will ask to perform four exercises utilizing large muscle groups (eg, leg press, shoulder press, chest press and pull ups). Intensity will determine during their first resistance exercise session using an established protocol. They will required to complete three sets of 12–15 repetitions during each exercise session. Each exercise session will be last about 20 to 30 minutes, depending on the individual's tolerance and fitness level. Frequency will be aimed for 2-3 sessions per week. This frequency allows for adequate recovery between sessions while providing enough stimulus to improve fitness over time. Mode and intensity of exercise will adjust monthly. Intervention 2: Control group: conventional therapy along with verbal advice about the cardiovascular and arthritis related benefits of exercise for the same period. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no further information
public Aqsa Riaz
95A Lda avenue 1, Raiwind road Lahore
Lahore Pakistan 54600 +92 42 35126110 aqsariaz246@gmail.com Riphah International University scientific Wajeeha zia
25 Raza saeed Rd, Bhabra Block M Gulberg III, Lahore.
Lahore Pakistan 54000 +92 42 35126110 wajeeha_z@yahoo.com Riphah international university Pakistan • Patient with RA Patients with sedentary lifestyle (no participation in structural exercise for thepreceding 6 months) RA factor positive Both males and females • Age between 40-65 years • Stable disease 40 years 65 years Both Joint surgery (in the preceding 6 months) Cognitive disability Other joint diseases such as Osteoporosis and Osteoarthritis Previous history of fracture • Primary neurological disease M06 Other rheumatoid arthritis Rehabilitation Rehabilitation Intervention group: Resistance exercise training: Patients will ask to perform four exercises utilizing large muscle groups (eg, leg press, shoulder press, chest press and pull ups). Intensity will determine during their first resistance exercise session using an established protocol. They will required to complete three sets of 12–15 repetitions during each exercise session. Each exercise session will be last about 20 to 30 minutes, depending on the individual's tolerance and fitness level. Frequency will be aimed for 2-3 sessions per week. This frequency allows for adequate recovery between sessions while providing enough stimulus to improve fitness over time. Mode and intensity of exercise will adjust monthly. Control group: conventional therapy along with verbal advice about the cardiovascular and arthritis related benefits of exercise for the same period Resistance training. Timepoint: Pre post treatment. Method of measurement: 6 minutes walk test,spirometry, blood test. Inflammatory markers. Timepoint: Pre post treatment. Method of measurement: Blood Test ( Complete Blood Count). Riphah international university Approved 2024-01-15 Riphah College of rehabilitation & Allied health sciences 25 Raza Saeed Rd, Bhabra block M Gulberg III, Lahore. Punjab Lahore Punjab Pakistan