IRCT20231226060527N1 IRCT 2024-10-01 Sanandaj University of Medical Sciences The effect of alphalipoic acid in nausea of ​​pregnancy CEAB6 Comparing the effect of alipoic acid with vitamin B6 in the treatment of pregnancy nausea and vomiting 2024-07-06 anticipated 80 Complete https://irct.ir/trial/77752 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization is based on the formation of Blocks of 4 and the random selection of each of these Blocks for every 4 new Patients entered, and the Blocks are as follows: AABB ABAB ABBA BBAA BABA BAAB First, the demographic and clinical information of the patients, including age, BMI, education, gestational age, number of births, type of pregnancy, history of nausea and vomiting during pregnancy will be collected based on the checklist (Appendix 1). Then, using random blocks of 4, the patients will be divided into two groups: 1) alpha lipoic acid and 2) vitamin B6, Blinding description: Due to the fact that the form of the drugs are not the same and the treating physician is one of the evaluators of the results, it is not possible to perform double blinding and the only person who performs the data analysis (data analyzer) will be blinded to the treatment groups. As a result, the study is one-sided blind. 3 Pregnancy Nausea and Vomiting. Intervention 1: Intervention group: vitamin B6 group (recipient of vitamin B6 tablets with a dose of 25 mg orally 3 times a day for one week). Intervention 2: Intervention group: Alpha-lipoic acid group (receiver of alpha-lipoic acid capsules with a dose of 300 mg orally, twice a day for one week). Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information