IRCT201511257297N2 IRCT 2015-12-12 shiraz university of medical science topical rose oil in the patients with migraine headache Efficacy and side effects of topical rose oil in the treatment of acute migraine headache 2015-04-21 anticipated 40 Other https://irct.ir/trial/7745 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Crossover, Purpose: Treatment, Other design features: basic demographic of patients, basic demographic of their headache, pain intensity of patients based on VAS before use and till 24hr after use of drug or placebo, intensity of their headache features such as nausea/vomiting,get away of light( photophobia), get away of sound with use of drug or placebo for 2hr, pain intensity in cold and hot temperament patients after use the drug or placebo. N/A migraine headache. Intervention 1: essential rose oil as a drug, 7cc, almost 2cc in every attack used topical in temporal and frontal area, interval of attacks was minimum 1 week as washout period. Intervention 2: Liquid paraffin as a placebo, 7cc, almost 2cc in every attack used topical in temporal and frontal area, interval of attacks was minimum 1 week as washout period.