<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20240211060958N2</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2024-06-02</date_registration>
      <primary_sponsor>Kerman University of Medical Sciences</primary_sponsor>
      <public_title>effect of neurodynamic mobilization and dry needling technique in subjects with  patellofemoral pain syndrome</public_title>
      <acronym>patellofemoral pain syndrome (PFPS)</acronym>
      <scientific_title>Comparison of the effect of neurodynamic mobilization and dry needling technique on the pain, function, and range of motion in subjects with  patellofemoral pain syndrome</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2024-06-21</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>120</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/76228</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Simple randomization: A table of random numbers is used. Participants are given a number and using the table of random numbers. Therapist randomly starts from a table point in the row or column direction. The therapist can close his eyes and choose a point, Blinding description: Double-blind study will be done ,in this way,  the assessment of patients are done by people who are unaware of the status of the grouping of patients. Treatment is provided by a specialist physiotherapist and evaluated by a collaborator.</study_design>
      <phase>3</phase>
      <hc_freetext>patellofemoral pain syndrome.</hc_freetext>
      <i_freetext>Intervention 1: Intervention group: Dry needling.                                                                 The treatment is done in 3 sessions with an interval of one day. The muscles selected for dry needling in this study are practically important in the management of patellofemoral syndrome, including: quadratus lumborum, gluteus medius, iliopsoas, rectus femoris, vastus medialis, and vastus lateralis. Intervention 2: Intervention group: Neuromobilization of femoral nerve                                The patient is placed in a sidelying position on the side of the healthy leg. The lower limb on the healthy side is placed at 90 degrees of hip flexion and knee flexion. The lower limb of the affected side is placed in a neutral hip position, and the trunk is in a straight position and the head is in a neutral position. The therapist stands behind the patient at the level of the pelvis so that the pelvis does not move forward or backward. Then we ask the patient to actively move neck and trunk flexion, knee extension to neck and trunk extension, knee flexion. Intervention 3: Control group: Placebo                                                                                       While the patient is supine position, the therapist applies soft and superficial massage on the involved muscles. The fingertips of each therapist's hand are placed in contact with the related muscles and a surface massage is performed. The number of sessions is the same as the dry needling group.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Yes - There is a plan to make this available</results_IPD_plan>
      <results_IPD_description>What will be shared:
Some of the data, such as information about the consequences, can be shared

When:
Starting the access period: 6 months after publition the results

To whom:
Researchers working in academic institutions

Conditions:
Only statistical analyzes can be used to find treatment for improvement of patients

Where to obtain:
Applicants can be guided by email to the authors(tahere.rezaiyan@gmail.com).

How to obtain:
First, they will email the authors of the study and we Will be answered within a week

Comments:
</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>tahereh rezaeian</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>The beginning of Haft Bagh Alavi axis, Kerman University of Medical Sciences</address>
        <city>kerman</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>7616913555</zip>
        <telephone>+98 34 3132 5700</telephone>
        <email>tahere.rezaiyan@gmail.com</email>
        <affiliation>Kerman University of Medical Sciences</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>tahereh rezaeian</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>The beginning of Haft Bagh Alavi axis, Kerman University of Medical Sciences</address>
        <city>kerman</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>7616913555</zip>
        <telephone>+98 34 3132 5700</telephone>
        <email>tahere.rezaiyan@gmail.com</email>
        <affiliation>Kerman University of Medical Sciences</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>All participants are aged from 18 to 40 years
Having a clinical diagnosis of patellofemoral syndrome.
Complaints of pain in the anterior of the knee or around the patella on the affected side are determined during at least 3 of the following activities: squatting, step up and down from stairs, running, prolonged sitting, and kneeling.
Positive Clark test
Unilateral pain in one knee
having constant pain for at least the last 4 weeks and the average pain in the last week is more than 3 according to the NPRS scale.
The present of trigger points in the gluteus medius and quadriceps muscles on the same side and quadratus lumborum on the opposite side.</inclusion_criteria>
      <agemin>18 years</agemin>
      <agemax>40 years</agemax>
      <gender>Both</gender>
      <exclusion_criteria>History of previous knee surgery
Any knee pathology (meniscus tear, patella tendinopathy, ligament sprain and osteoarthritis)
Any systemic diseases and/or connective tissue disorders
People who have received acupuncture, injections, or dry needling treatment for knee in the past 6 months.
Pregnant women</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>M25.56</hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword>Pain in knee</hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Rehabilitation</i_code>
      <i_code>Rehabilitation</i_code>
      <i_code>Placebo</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention group: Dry needling.                                                                 The treatment is done in 3 sessions with an interval of one day. The muscles selected for dry needling in this study are practically important in the management of patellofemoral syndrome, including: quadratus lumborum, gluteus medius, iliopsoas, rectus femoris, vastus medialis, and vastus lateralis.</i_keyword>
      <i_keyword>Intervention group: Neuromobilization of femoral nerve                                The patient is placed in a sidelying position on the side of the healthy leg. The lower limb on the healthy side is placed at 90 degrees of hip flexion and knee flexion. The lower limb of the affected side is placed in a neutral hip position, and the trunk is in a straight position and the head is in a neutral position. The therapist stands behind the patient at the level of the pelvis so that the pelvis does not move forward or backward. Then we ask the patient to actively move neck and trunk flexion, knee extension to neck and trunk extension, knee flexion.</i_keyword>
      <i_keyword>Control group: Placebo                                                                                       While the patient is supine position, the therapist applies soft and superficial massage on the involved muscles. The fingertips of each therapist's hand are placed in contact with the related muscles and a surface massage is performed. The number of sessions is the same as the dry needling group.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Pain intensity. Timepoint: Before, After and 1month follow up. Method of measurement: Visual analog scale.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome>Knee disability index. Timepoint: Before, After and 1month follow up. Method of measurement: kujala questionnaire.</sec_outcome>
      <sec_outcome>Step down test. Timepoint: Before, after and 1month follow up. Method of measurement: Functional test: Participants are asked to stand on the step with their injured foot, try to touch the ground with the opposite heel, and then return to their original position.</sec_outcome>
      <sec_outcome>Knee range of motion. Timepoint: Before, after and 1month follow up. Method of measurement: Goniometer.</sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Kerman University of Medical Sciences</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2024-02-08</approval_date>
        <contact_name>Ethics Committee of the kerman University of Medical Sciences</contact_name>
        <contact_address>Haft Bagh Square, Kerman University of Medical Sciences Kerman Kerman Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
