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IRCT20240211060958N1 IRCT 2024-05-15 Kerman University of Medical Sciences Effect of platelet-rich plasma and knee mobilization techniques and dry needling in knee osteoarthritis patients PRP(platelet-rich plasma) Comparison of the effect of platelet-rich plasma and knee mobilization techniques and dry needling in knee osteoarthritis patients 2024-06-21 anticipated 76 Complete https://irct.ir/trial/76225 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Block Randomization: It works by randomizing participants within blocks such that an equal number are assigned to each treatment. For example, given a block size of 10, there are 8 possible ways to equally assign participants to a block, Blinding description: Double-blind study will be done, in this way, the allocation of people to the groups and the assessment of patients are done by people who are unaware of the status of the grouping of patients. Treatment is provided by a specialist physiotherapist and evaluated by a collaborator. 3 knee osteoarthritis. Intervention 1: Intervention group: dry needling and knee mobilization. Intervention 2: Intervention group: platelet-rich plasma. Intervention 3: Control group: placebo. Yes - There is a plan to make this available What will be shared: Some of the data, such as information about the consequences, can be shared When: Starting the access period: 6 months after publiton the results To whom: Researchers working in academic institutions Conditions: Only statistical analyzes can be used to find treatment for improvement of patients Where to obtain: Applicants can be guided by email's responsible author. (tahere.rezaiyan@gmail.com) How to obtain: First, they will email the responsible author of the study and we Will be answered within a week.(Applicants can be guided by email's responsible author. tahere.rezaiyan@gmail.com) Comments:
public Tahereh Rezaeian
Kerman University of Medical Sciences, Haft Bagh Square, Kerman Town
Kerman Iran (Islamic Republic of) 7616913555 +98 34 3132 5700 tahere.rezaiyan@gmail.com Kerman University of Medical Sciences scientific Tahereh Rezaeian
Kerman University of Medical Sciences, Haft Bagh Square, Kerman Town
Kerman Iran (Islamic Republic of) 7616913555 +98 34 3132 5700 Tahere.rezaiyan@gmail.com Kerman University of Medical Sciences Iran (Islamic Republic of) The patients were between the ages of 45 and 70 years old The presence of moderate osteoarthritis symptoms (grade 2-3 of the Kellgren-Lawrence classification system) The presence of trigger point (latent or active) in the muscles around the hip and knee joints. 45 years 70 years Both Patients with severe inflammation/swelling of the knee Any history of injection/aspiration of the knee joint during the last year Any previous fracture of the spine or lower limbs Associated neurological pathology Vestibular disorders Systemic disease (rheumatoid arthritis or diabetes) Patients with blood disorders (such as hemophilia or thalassemia), cancer, or if they are taking taking anticoagulants drugs M17.0 Bilateral primary osteoarthritis of knee Rehabilitation Treatment - Other Rehabilitation Intervention group: dry needling and knee mobilization Intervention group: platelet-rich plasma Control group: placebo 1.Pain intensity. Timepoint: Before, After and 2month follow up. Method of measurement: Visual analog scale. Knee disability index. Timepoint: Before, After and 2month follow up. Method of measurement: WOMAC questionnaire and KOOS questionnaire. Knee range of motion. Timepoint: Before, After and 2month follow up. Method of measurement: Goniometer. Kerman University of Medical Sciences Approved 2023-12-11 Kerman University of Medical Sciences Kerman University of Medical Sciences, Haft Bagh Square, Kerman Town Kerman Kerman Iran (Islamic Republic of)