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IRCT201601137128N6 IRCT 2016-04-26 vice chancellor for research of tabriz university of medical sciences Effect of non-surgical periodontal therapy on serum level of transferrin and clinical parameters in patients with periodontal disease Effect of non-surgical periodontal therapy on serum transferrin levels in chronic periodontitis patients 2015-04-05 anticipated 40 Complete https://irct.ir/trial/7553 interventional Randomization: Not randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A Chronic periodontitis. Intervention 1: Intervention: chronic periodontitis : Patients in the chronic periodontitis group received nonsurgical periodontal therapy, including oral hygiene instructions(flossing & brushing with Bass technique), and scaling and root planing in one 1hour session.then, 0.12 % chlorhexidine mouthwash(Cosmodent Co.,Gingival KIN,spain) was prescribed for 14 days(15ml for 30seconds twice a day). Intervention 2: Control: healthy periodontal control group subjects were provided with oral hygiene instructions(flossing & brushing with Bass technique) only in 1 20minute session.
public ashkan salari
Tabriz ,Golgasht street,Dentistry faculty
Tabriz Iran (Islamic Republic of) 5166614711 +98 41 1335 5965 drashkan_salari@yahoo.com Tabriz university of medical science scientific Adileh shirmohammadi
Tabriz-Golgasht street- Dentistry faculty
Tabriz Iran (Islamic Republic of) 5166614711 +98 41 1335 5965 shirmohamadia@tbzmed.ac.ir Tabriz university of medical science Iran (Islamic Republic of) inclusion criteria in periodontally healthy group:no evidence of interproximal attachment loss, no PD equal or more than 3mm at any sites on any teeth and whole-mouth bleeding scores equal or less than 10%. inclusion criteria in chronic periodontitis group: two or more interproximal sites with attachment loss equal or more than 4mm, or two or more interproximal sites with PD equal or more 5mm,not on same tooth. Exclusion criteria :1) a course of NSAIDs or antimicrobial drugs within a 6 month period before the study 2)history of any periodontal treatment within a 6 month period before the study 3) presence of any systemic disease and infection other than chronic periodontitis 4)presence of aggressive periodontitis 5)pregnancy or lactating mothers 6) use of mouthwashes or vitamin supplements within the previous 3 months 7) furca involvement grade 2 , 3 , 4 25 years 60 years Both K05.3 Chronic periodontitis Treatment - Other N/A Intervention: chronic periodontitis : Patients in the chronic periodontitis group received nonsurgical periodontal therapy, including oral hygiene instructions(flossing & brushing with Bass technique), and scaling and root planing in one 1hour session.then, 0.12 % chlorhexidine mouthwash(Cosmodent Co.,Gingival KIN,spain) was prescribed for 14 days(15ml for 30seconds twice a day). Control: healthy periodontal control group subjects were provided with oral hygiene instructions(flossing & brushing with Bass technique) only in 1 20minute session Serum level of transferrin. Timepoint: Base line-3month. Method of measurement: laboratory test. Clinical parameters of periodontium. Timepoint: Base line-3month. Method of measurement: periodontal probing. vice chancellor for research of tabriz university of medical sciences Approved 2016-01-13 Ethics committee Tabriz univercity of medical science Golgasht street,daneshgah street,Tabriz Tabriz Iran (Islamic Republic of)