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IRCT201211277128N3 IRCT 2012-12-23 Tabriz University of Medical Science Comparision of the effect of photodynamic therapy associated with scaling and scaling alone in aggrissive gingival disease Comparision of the clinical and microbiological effects of photodynamic therapy as an adjunctive treatment with scaling and root planning with scaling and root planning alone in aggressive periodontitis 2012-07-22 anticipated 28 Complete https://irct.ir/trial/7550 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A aggresive periodontitis. Intervention 1: control: scaling and rootplanning as full mouth approach in all quadrants. Intervention 2: intervention: Scaling and root planning with photodynamic teraphy in the selected teeth with PD≥4mm after application of photosensitizer and then the irradition of the laser with wavelength 670-690 nm with energy of 75 mW/cm2 for 120 seconds.
public Dr Ilnaz Farhoudi
Daneshgah street, Golgasht, Tabriz
Tabriz Iran (Islamic Republic of) 5166614711 +98 41 1335 5966 shirmohamadia@tbzmed.ac.irelnaz.farhoodi@yahoo.com Tabriz University of Medical Science scientific Dr Adileh Shirmohamadi
Periodontics ward of Dentistry faculty, Daneshgah street, Golgasht
Tabriz Iran (Islamic Republic of) 5166614711 +98 41 1334 6977 shirmohamadia@tbzmed.ac.irelnaz.farhoodi@yahoo.com Tabriz University of Medical Science Iran (Islamic Republic of) Inclusion criteria: A total of 28 patients; with an age range of 18-45 years, suffering from aggressive periodontitis; The subjects had at least 12 teeth and at least 3 teeth in each quadrant and one tooth with CAL≥4mm in each quadrant. Exclusion criteria: systemic disease; conditions which delay would healing; a history of radiotherapy or immune-suppressive treatment modalities; pregnancy or breast-feeling; use of systemic antibiotics during the 6 previous months; history of scaling and root planning during the previous year. 18 years 45 years Both K05.4 Peri Juvenile periodontosis Treatment - Other Treatment - Other control: scaling and rootplanning as full mouth approach in all quadrants intervention: Scaling and root planning with photodynamic teraphy in the selected teeth with PD≥4mm after application of photosensitizer and then the irradition of the laser with wavelength 670-690 nm with energy of 75 mW/cm2 for 120 seconds Clinical attachment level (CAL). Timepoint: baseline and 3 month later. Method of measurement: milimeter distance from CEJ to bottom of pocket with a periodontal probe. Probing Depth (PD). Timepoint: baseline and 3 month later. Method of measurement: milimeter distance from gingival margin to botom of pocket. Bleeding on probing (BOP). Timepoint: baseline and 3 month later. Method of measurement: presence or absence of bleeding 30 s after probing. Recession (REC). Timepoint: baseline and 3 month later. Method of measurement: milimeter distance from CEJ to gingival margin. Plaque Index (PI). Timepoint: baseline and 3 month later. Method of measurement: Oleary Plaque Index. Gingival Index(GI). Timepoint: baseline and 3 month later. Method of measurement: Loe & Silness introduced it base on imflamation and ademe and redness and important object of it, is bleeding. Quantitive measurment of Aa (Aggregatibacter actinomycetemcomitans). Timepoint: baseline and 3 month later. Method of measurement: real time PCR by special laboratory kits of real-time PCR. Tabriz University of Medical Science Approved 2012-10-20 Ethics committee of Tabriz University of Medical Science Dentistry Faculty, Daneshgah St, Golgasht Tabriz Iran (Islamic Republic of)