IRCT20240128060832N1 IRCT 2024-02-24 Ahvaz University of Medical Sciences Investigating the effect of moxifloxacin in Helicobacter infection Comparison of effectiveness of moxifloxacin, amoxicillin and pantoprazole regimen with clarithromycin-based four-drug regimen for eradicating Helicobacter pylori infection 2024-03-20 anticipated 246 Complete https://irct.ir/trial/75425 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: People will be divided into two groups based on the first quadruple random permutation completely randomly (by a person who had no involvement in the study process). Also, matching will be done based on age and gender, Blinding description: Blinding is done in such a way that the person who performs the randomization and allocation of people to groups will not have any information about the condition of the patients. The patient and the person who examines the results will not have any information about which group the people are placed in, and the study is conducted in a double-blind manner. 3 Helicobacter pylori infection. Intervention 1: Intervention group: Administration of amoxicillin 1000 mg every 12 hours, moxifloxacin 400 mg every 12 hours, and pantoprazole 40 mg every 12 hours for 10 days, followed by pantoprazole at a dose of 40 mg every twelve hours for four weeks. Intervention 2: Control group: Administration of clarithromycin 500 mg every 12 hours, amoxicillin 1000 mg every 12 hours, bismuth subcitrate 240 mg every 12 hours and pantoprazole 40 mg every 12 hours for 10 days, followed by pantoprazole at a dose of 40 mg every twelve hours. The watch lasts for four weeks. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information