IRCT20100127003213N11 IRCT 2024-01-28 Shiraz University of Medical Sciences Glossopharyngeal nerve block compared to Ropivacaine infiltration in improving tonsillectomy pain in children. Glossopharyngeal nerve block compared to Ropivacaine infiltration as part of a multimodal analgesic regimen for post tonsillectomy pain relief in children A randomized controlled clinical study 2024-03-01 anticipated 90 Complete https://irct.ir/trial/74951 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Patients will be randomly allocated into three groups by block randomization. In this technique, a permutation block of size 6 will be made for patients of two groups G,R & C. In each block, equal numbers for three groups will be considered in alternative positions. Then 15 blocks of size 6 will be selected randomly and patients will be allocated randomly and equally into three groups according to these permutation block. block sequence will be prepare by www.sealedenvelope.com, Blinding description: In group G, the surgeon will inject 5 ml of 0.2% ropivacaine solution in the glossopharyngeal block. In group R, the surgeon will inject 5 ml of 0.2% ropivacaine solution in the tonsil cavity and its surrounding areas. In group C, at the end of the operation, in order to blind the study in half of the group (15 people), similar to the intervention group (G), the glossopharyngeal nerve block was performed by the surgeon using a placebo (0.9% normal saline) and in 15 people Another group, similar to group (R), is infiltration in the tonsil cavity with a placebo (0.9% normal saline solution). In the operating room, all study drugs will be provided by the only person familiar with the study (Nurse anesthetist). The anesthesiologist, patients, and other personnel involved in the work are blinded to the drugs injected in this study. This study is double-blind. 2-3 Tonsillectomy. Intervention 1: Intervention group (G) : In all three groups, after the induction of anesthesia, the patients receive intravenous drugs of the studied analgesic regimen, which includes 500 μg/kg of ketamine and 150 μg/kg of dexamethasone. All surgeries will be performed by an otolaryngologist and cold dissection with ligature method. At the end of the surgery, in group (G), the surgeon injects 5 ml of 0.2% ropivacaine solution on each side of the glossopharyngeal nerve block. (Using a size 25 spinal needle at a 45 degree angle, it is inserted into the middle part of the palatopharyngeal fold in the back mucosa tissue of the pharynx, and then with a depth of 0.5 cm in the back wall of the pharynx, after negative aspiration, the injection is performed). Intervention 2: Intervention group (R) : At the end of surgery, in group (R), The surgeon w injects 5 ml of 0.2% Ropivacaine solution in the tonsil cavity and its surrounding areas after negative aspiration. Intervention 3: Control group (C) : After the induction of anesthesia, in addition to receiving intravenous drugs for the studied analgesic regimen, which is common in all groups, the basic analgesic regimen includes Paracetamol at the rate of 15 mg/kg and ketorolac at the rate of 470 μg/kg. receive intravenously and in order to blind the study, In group C, at the end of the operation, 15 people, similar to the intervention group (G), and another 15 people, similar to the intervention group (R), were injected using a placebo (0.9% normal saline). No - There is not a plan to make this available Justification or reason for not sharing IPD is It is against our policy.