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IRCT20151123025202N36 IRCT 2024-02-12 Hamedan University of Medical Sciences Effect of pregabalin on postoperative thyroidectomy pain Comparison of the effectiveness of pregabalin and placebo on post thyroidectomy pain of patients with thyroid carcinoma 2024-02-20 anticipated 30 Complete https://irct.ir/trial/74949 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: We made 30 cards and write letter A on 15 and B on the others. Then put them inside the envelope with aluminum wrap and put in a box. At the time of patient arrival, one of the envelopes randomly will be selected and open it, based on selected letter (A or B) patients will be assigned to Pregabalin or Placebo group, Blinding description: In this study, pregabalin and placebo will be packed inside the capsule in the same shape and color with different codes. The person who prescribes the medicine and the person who evaluates the pain score and satisfaction of the patients will not know about the contents of the capsules (double-blind). 3 Thyroid carcinoma. Intervention 1: Intervention group: One hour before the operation, they will receive single dose of 150 mg oral pregabalin capsule. Intervention 2: Control group: One hour before the operation, they will receive single dose of oral capsules containing placebo. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information
public Abbas Moradi
Medical School, Shahid Fahmideh Ave, Hamadan
Hamadan Iran (Islamic Republic of) 6517838736 +98 81 3838 0572 a.moradi@umsha.ac.ir Hamedan University of Medical Sciences scientific Ruholah Abbasi
Medical School, Shahid Fahmideh Ave, Hamadan
Hamadan Iran (Islamic Republic of) 6517838736 +98 81 3838 0557 Ruholah@abasihatmil.com Hamedan University of Medical Sciences Iran (Islamic Republic of) Patients undergoing thyroidectomy surgery Being at the age of 20-60 years Weight of 40 to 80 kg Having consent to participate in the study 20 years 60 years Both History of any drug allergy D09.3 Carcinoma in situ of thyroid and other endocrine glands Treatment - Drugs Treatment - Other Intervention group: One hour before the operation, they will receive single dose of 150 mg oral pregabalin capsule. Control group: One hour before the operation, they will receive single dose of oral capsules containing placebo. Postoperative pain Severity. Timepoint: 6 hours after the operation. Method of measurement: with Visual Analogue Score. The amount of analgesic use. Timepoint: 6 hours after the operation. Method of measurement: patient's medical record. Nausea. Timepoint: 6 hours after the operation. Method of measurement: Ask the patient. Vomiting. Timepoint: 6 hours after the operation. Method of measurement: Ask the patient. Dizziness. Timepoint: 6 hours after the operation. Method of measurement: Ask the patient. Hamedan University of Medical Sciences Approved 2024-01-20 Ethics committee of Hamadan Univercity of Medical Sciences ُShahid Fahmideh Avenue Hamadan Hamadan Iran (Islamic Republic of)