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IRCT20240107060637N1 IRCT 2024-01-28 Shiraz University of Medical Sciences the effect of Citicoline on the retina in Non-Arteritic Anterior Ischemic Optic Neuropathy The study of Optical coherence tomography and Optical coherence tomography angiography of the patients with Non-Arteritic Anterior Ischemic Optic Neuropathy before and after receiving Citicoline 2024-01-10 anticipated 20 Complete https://irct.ir/trial/74880 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment. 2 Non-Arteritic Anterior Ischemic Optic Neuropathy. Intervention group: In this group, Citicoline ampule with a dose of 500 mg is injected intramuscularly once a week for 3 weeks.. Yes - There is a plan to make this available What will be shared: Information about the main outcome is shared after making people unidentifiable. When: Starting the access period from the date of publication of the results up to 5 years later To whom: Researchers and people working in the pharmaceutical industry Conditions: Those who intend to produce, prescribe and research this drug Where to obtain: khalilimr57@gmail.com Dr Mohammadreza Khalili How to obtain: Examination and receiving of medication by patients for one month Collecting OCTA and OCT photos for one month. Comments:
public Mohammad reza Khalili
Zand St., Stad block, in front of the Medical School, Poostachi Ophthalmology Research Center
Shiraz Iran (Islamic Republic of) 7134997446 +98 71 3230 2830 khalilimr57@gmail.com Shiraz University of Medical Sciences scientific Mohammad reza Khalili
Zand St., Stad block, in front of the Medical School, Poostachi Ophthalmology Research Center
Shiraz Iran (Islamic Republic of) 7134997446 +98 71 3230 2830 khalilimr57@gmail.com Shiraz University of Medical Sciences Iran (Islamic Republic of) The patient is in the first week of the attack Age: Older than 18 years 18 years no limit Both Consumption of Citicoline in the last three months as well as antioxidants and multivitamins and having a special diet Receiving previous treatment Congenital and acquired retinal diseases Presence of ocular pathology such as glaucoma, retinal disease and uveitis Taking corticosteroid drugs Taking Levodopa Treatment - Drugs Intervention group: In this group, Citicoline ampule with a dose of 500 mg is injected intramuscularly once a week for 3 weeks. The amount of damage in the thickness of the ganglion cell layer and optic nerve fiber layer is reduced in OCT images of the patient before and after receiving citicoline.2. Vascular density in OCTA should not be reduced. Timepoint: Patients will undergo paraclinical examinations during the first week of AION attack and one month after the start of treatment. Method of measurement: Optical coherence tomography and Optical coherence tomography angiography. Shiraz University of Medical Sciences Approved 2024-01-03 Ethics committee of Shiraz University of Medical Sciences Shiraz University of Medical Sciences, Zand St Shiraz Fars Iran (Islamic Republic of)