IRCT20200408046990N15 IRCT 2024-01-03 Mashhad University of Medical Sciences Evaluation of pomegranate peel extract in bladder infection Evaluation of the oral formulation of pomegranate peel extract efficacy for the treatment of cystitis 2024-01-21 anticipated 40 Complete https://irct.ir/trial/74439 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: This study will use the block randomization method to generate a sequence of random numbers. In this method, eight blocks of size 4 and 4 blocks of size two are randomly selected from the combination of letters A and B with a table of random numbers. The list of blocks of size two is 1:AB, 2:BA, and the list of blocks of size four is: 1:AABB, 2:ABBA, 3:BBAA, 4:BAAB, 5:BABA, 6:ABAB. To select blocks of size 2, 4 numbers are randomly selected from the table of random numbers. If this number is from 0 to 4, the first block is selected, and if the number is from 5 to 9, the second block is selected. To select blocks of size 4, 8 numbers between 1 and 6 are randomly selected from the table of random numbers. Then, if this number is 1, the first block of size 4, and if the chosen number is 2, the second block and so on are selected, Blinding description: In this study, the method of triple blinding includes the participants themselves, the outcome assessor (including the pharmacist), and the clinical supervisor (specialist doctor). The people mentioned in this study do not know about the type of medicine, either placebo or medicinal substance. The person who prepares the study's draft (pharmacist) needs to learn the nature of the substance used. 3 Cystitis. Intervention 1: Intervention group: The intervention group will receive capsules containing 250 mg of pomegranate peel extract three times a day for one week. Intervention 2: Control group: The control group will receive placebo capsules containing lactose three times a day for one week. Yes - There is a plan to make this available What will be shared: The findings will be published in an article. Study protocol and statistical analysis will be used for article publication. When: One year after the end of the study it will be published and available in databases. To whom: The findings will be available for researchers, clinicians, and scientific centers if the funding sponsor allows. Conditions: The other researchers can use our findings in their review articles and meta analysis. Where to obtain: For this purpose, you can contact with Sepideh Elyasi, at Clinical Pharmacy Department, School of Pharmacy, Vakil Abad Aven., Mashhad, Iran. Email: elyasis@mums.ac.ir How to obtain: After receiving the query, dependent on the requested data, the scientific responsible person of the study will response to the query in coordinate with the sponsor within 2 weeks. Comments: