IRCT20210308050628N1 IRCT 2023-12-08 Hamedan University of Medical Sciences Investigating the effect of neoadjuvant chemotherapy on locally advanced rectal cancer The Assessment of Efficacy for Neoadjuvant Chemotherapy with Modified FOLFOX6 compared to Chemoradiation for the Management of Locally Advanced Rectal Cancer: A Promising Therapeutic Approach 2015-01-10 anticipated 300 Complete https://irct.ir/trial/74183 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: The patients referred to the Cancer center after essential and necessary task, entered the intervention and control group respectively. In other word, odds number entered intervention group and even numbers entered control group, Blinding description: Patients had no role in selecting treatment type. Pathologists and Surgeons did not know the treatment type. The analysis team did not know the type of treatment. 3 Locally advanced Rectal cancers. Intervention group: َییهدل دثخشیتعرشدف زاثئخفاثقشحغ. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information