IRCT20160523028008N29 IRCT 2023-12-02 Hamedan University of Medical Sciences Indomethacin suppositories on pregnancy outcomes in IVF The Investigating of effect indomethacin suppositories on pregnancy outcomes in IVF candidates with a history of more than two failed embryo transfers. 2023-12-15 anticipated 120 Complete https://irct.ir/trial/74063 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Block randomization will randomly assign the cases to intervention and control groups. For this purpose, we will prepare four sheets of paper, writing on two sheets the name of the intervention and on the other two sheets the name of the control. The paper sheets will be pooled, placed in a container, and randomly drawn one at a time for each patient without replacement until all four sheets are removed. The four paper sheets will be then placed back into the container, and this action will be repeated until the sample size is reached, Blinding description: The person who examines patients for outcomes is not informed of the allocation of patients to the intervention and control groups. 2-3 Female infertility. Intervention 1: Intervention group: Patients in the transfer cycle are given Suppression (FET long) and then receive 100 mg Indomethacin suppositories made by Darou Pakhsh-Iran one hour before embryo transfer and 12 hours after the first dose. Then both groups continue their transfer medications uniformly according to the protocol, and 14-12 days after the transfer, a pregnancy test is performed. If it is positive, an ultrasound is performed for pregnancy sac and fetal heart at weeks 6 and 8. Intervention 2: Control group: This group receives the same intervention protocol without receiving indomethacin. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is not a plan to make this available