IRCT20220508054780N3 IRCT 2023-12-01 Mashhad University of Medical Sciences The effectiveness of Allicin on survival of sepsis patients in intensive care units A clinical trial to compare the effectiveness of Allicin with placebo on survival of sepsis patients in intensive care units 2024-01-21 anticipated 110 Complete https://irct.ir/trial/74040 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Patients will be simple randomly assigned to two groups using the blocks and opaque envelopes will be used for concealment, Blinding description: The participants and responsible for data collection are blind to group allocation and the type of intervention. 1-2 Sepsis. Intervention 1: Intervention group: The intervention group will receive 90 mg capsules of Nicovid, which is derived from Organosulfur (Daghigh Tajhiz Ario, Tehran, Iran), orally every 6 hours for 7 days. Intervention 2: Control group: The control group will receive placebo (There is no Organosulfur in it, but it has the same color, taste, structure and shape as Nicovid, produced by the research center of faculty of pharmacy, Mashhad University of Medical Sciences) orally every 6 hours for 7 days. Yes - There is a plan to make this available What will be shared: The research data obtained from the main outcomes of the study can be shared freely as 'open data'. When: 6 months after publishing the results To whom: The research data is exclusively accessible to the researchers working at universities and centers for scientific research. Conditions: The research data is exclusively accessible to the researchers working at universities and centers for scientific research. Where to obtain: Benyamin Fazli provides the data analysis to the applicants via email: fazlib@mums.ac.ir How to obtain: Applicants can send emails to him and receive a response within a week. Comments: