IRCT20231126060189N1 IRCT 2024-01-23 Birjand University of Medical Sciences Evaluation of the effect of Zataria multiflora extract mouthwash on prevention of chemotherapy induced oral mucositis Evaluation of the effectiveness of Zataria multiflora extract mouthwash on prevention of chemotherapy induced oral mucositis In patients undergoing chemotherapy 2024-02-19 anticipated 78 Complete https://irct.ir/trial/73996 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: Block randomization. After sampling, using "R" statistical software, individuals without clustering are placed in the placebo and intervention groups through block randomization with block size of 8, so that the size of the two groups is equal, Blinding description: A person outside the study codes the mouthwash and placebo, and a code is assigned to each patient. Until the end of the study, the researcher,the evaluator and the participants will not know in which category they have been placed. The placebo contains all the ingredients of intervention mouthwash except Zataria multiflora. The placebo will be the same color as the intervention mouthwash and will be odorless. The packaging of placebo and intervention mouthwash will be the same. 3 chemotherapy induced oral mucositis. Intervention 1: Intervention group: For 21 days, three times a day and half an hour before chemotherapy, they gargle 5 ml of Protect containing Zataria Multiflora(Zulang Respina Pharmaceutical Company) mouthwash for 1 minute. Intervention 2: Control group: Intervention group: For 21 days, three times a day and half an hour before chemotherapy, they gargle 5 ml of placebo mouthwash for 1 minute. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information