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IRCT20230726058930N2 IRCT 2023-11-18 Ahvaz University of Medical Sciences Evaluation of the effect of magnesium sulfate in renal colic patients Evaluation of the effect of magnesium sulfate on the intensity and duration of pain in renal colic patients by a double-blind clinical trial in the case and control groups 2023-11-11 anticipated 160 Complete https://irct.ir/trial/73555 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Patients are randomly divided into two groups using the balanced block randomization technique. For this purpose, blocks of four are prepared, the name of the witness is written on two sheets and the interventionist's name is written on the other two sheets. The sheets are piled up and placed in the container, and one sheet is pulled out for each patient without placing it. Then four sheets are returned to the container and this process is repeated until the sample volume is reached, Blinding description: The student researcher conducting the research who is responsible for data collection and the patients participating in this research were kept blinded. The emergency doctor and nurses know the difference between the control group and the intervention group. Patients will be adequately explained about the trial and will be excluded from the study if they do not wish to participate. After the patient's discharge, the research student will be informed about the medicine received by the patient. 3 renal colic. Intervention 1: Intervention group: A dose of 30 mg of Ketorolac from Abidi Company plus 15 mg/kg of 50% magnesium sulfate from Shahid Ghazi Pharmaceuticals Company in 500 ml of normal saline is injected in 15 minutes. Intervention 2: Control group: patients receive 30 mg Ketorolac from Abidi Company and 30 ml of normal saline as a placebo in 500 ml of normal saline. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information
public Ali Vefagh Nematollahi
Imam Khomeini Hospital, Razi Hospital Ahvaz Jundishapur University of Medical Sciences
Ahvaz Iran (Islamic Republic of) 6135716794 +98 61 3367 5436 vefagh.a@ajums.ac.ir Ahvaz University of Medical Sciences scientific Ali Vefagh Nematollahi
Imam Khomeini Hospital, Razi Hospital Ahvaz Jundishapur University of Medical Sciences
Ahvaz Iran (Islamic Republic of) 6135716794 +98 61 3367 5436 vefagh.a@ajums.ac.ir Ahvaz University of Medical Sciences Iran (Islamic Republic of) Clinical diagnosis of renal colic Age between 18 and 55 years Having a pain intensity > 5 based on the analog vision scale (VAS) 18 years 55 years Both History of seizures Any heart, liver, kidney or metabolic disease Fever (oral temperature > 38 degrees Celsius) Systolic blood pressure less than 90 mm Hg pregnancy acute abdomen Taking pargoric medicine 3 hours before going to the emergency room History of drug addiction or allergy Taking calcium channel blockers Recent gastrointestinal bleeding, active peptic ulcer or recent perforation N23 Unspecified renal colic Treatment - Drugs Treatment - Drugs Intervention group: A dose of 30 mg of Ketorolac from Abidi Company plus 15 mg/kg of 50% magnesium sulfate from Shahid Ghazi Pharmaceuticals Company in 500 ml of normal saline is injected in 15 minutes. Control group: patients receive 30 mg Ketorolac from Abidi Company and 30 ml of normal saline as a placebo in 500 ml of normal saline. Intensity of pain. Timepoint: 0, 30 and 60 minutes after starting the drug. Method of measurement: Visual Analogue Scale. Systolic blood pressure. Timepoint: 0, 30 and 60 minutes after starting the drug. Method of measurement: Electronic sphygmomanometer. Diastolic blood pressure. Timepoint: 0, 30 and 60 minutes after starting the drug. Method of measurement: Electronic sphygmomanometer. Age. Timepoint: upon arrival. Method of measurement: Based on the patient's date of birth. Ahvaz University of Medical Sciences Approved 2023-08-26 Research ethics committees of Ahbaz Jundishapur University of Medical Sciences No. 385, Oribehesht St. Golestan Ahvaz Khouzestan Iran (Islamic Republic of)