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IRCT201106296917N1 IRCT 2015-10-12 Iran University of Medical Sciences- Sarem Hospital The impact of vitamins and antioxidants on the severity of endometriosis, pelvic pain in women Effects of vitamin E and C supplements on serum levels of biomarkers of oxidative stress and pelvic pain in women with endometriosis symptoms 2015-06-21 anticipated Complete https://irct.ir/trial/7346 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Other design features: By random method of packaging the door closed, that even numbers in a group and odd numbers in another group. N/A endometriosis. Intervention 1: Intervention group 1: In this study, the purpose of oral administration of vitamin E 800 units (two tablets of 400 IU) twice a day for 8 weeks and vitamin c tablets a day to 1000 mg (4 tablets of 250 mg) 4 times day for 8 weeks. Intervention 2: Control group: Taking 2 pills placebo vitamin E (400 IU) and 800 units of 4 placebo vitamin C (250 mg), a total of 1000 mg daily for 8 weeks.
public chekini razieh
School of Nursing and Midwifery, Iran University of Medical Science, Rashid Yasemi street, Vanak Square
Tehran Iran (Islamic Republic of) +98 21 8888 2886 r.chekini@gmail .com Iran University of Medical Sciences, School of Nursing and Midwifery scientific Dr Leila Amini
School of Nursing and Midwifery, Iran University of Medical Sciences, Rashid Yasemi Street, Vanak square
Tehran Iran (Islamic Republic of) +98 21 8888 2886 l-amini@iums.ac.ir School of Nursing and Midwifery, Iran University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: No current infection or a history of pelvic inflammatory disease during the study; Adenomyosis of disease, lack of supplementation in the last six months, not smoking, alcohol, lack of underlying chronic disease or mental illness known to his remarks patient, not a specific diet) such as a vegetarian diet); women with dysmenorrhea, irregular menstruation, lack of passing clots during menstruation. Exclusion criteria from the study: The patient's unwillingness to continue the research, side effects and drug allergy (such as fatigue, headache, blurred vision, nausea, diarrhea), the occurrence of pregnancy, diagnosed in the laparoscopy Adenomyosis 15 years 45 years Female n80 n80.9 Placebo Treatment - Drugs Intervention group 1: In this study, the purpose of oral administration of vitamin E 800 units (two tablets of 400 IU) twice a day for 8 weeks and vitamin c tablets a day to 1000 mg (4 tablets of 250 mg) 4 times day for 8 weeks. Control group: Taking 2 pills placebo vitamin E (400 IU) and 800 units of 4 placebo vitamin C (250 mg), a total of 1000 mg daily for 8 weeks. Bio-markers of oxidative stress. Timepoint: Two months before the intervention and after intervention. Method of measurement: Biomarker of oxidative stress in vitro assay kit. Severe pelvic pain. Timepoint: bi-weekly. Method of measurement: Visual analogue instruments. Iran University of Medical Sciences- Sarem Hospital Approved 2015-04-04 Ethics committee of Iran University of Medical Sciences Iran University of Medical Sciences, Intersection of Sheikh Fazlollah Nouri and Shahid Chamran, Shahid Hemat Highway Tehran Iran (Islamic Republic of)