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IRCT20230930059562N1 IRCT 2023-10-06 Imam hossein hospital Effect of interfron in the treatment of covid Effect of interfron in the treatment of covid 2021-01-21 anticipated 80 Complete https://irct.ir/trial/72881 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: A simple randomization method using a table of random numbers Patients with a positive PCR test who were volunteered to participate in the project were included in the project Each patient was assigned a random code Kendall's table was designed by the computer, which has rows and columns, and the computer itself put numbers side each other randomly, a row and a column were randomly selected, and the intersection point of the row and column was sampled as the starting point. then the plus sign was drawn and all the numbers that were on it were selected as sample members of the intervention group. This process continued until 40 people were selected and other people were placed in the control group, Blinding description: The patients were divided into two groups of 40 people, and the first intervention group received interferon beta in addition to the usual medical regime of Corona (Hydroxychlorquine and kaletra) and the second group (control) only received the usual medical regime. None of the groups knew which category they were in. has it The patients received the drugs in the form of packs by one of the colleagues of the project and were blinded to the drugs in the pack. 3 Covid pneumonia. Intervention 1: "Intervention group:" people receiving recigen brand interferon beta with a dose of 12m iu eq daily for 5 days along with other common corona treatments including hydroxychloroquine 200 every 12 hours and kletra 400 (ritonavir/lopinavir) daily​. Intervention 2: : "Control group: "Hydroxychloroquine 200 mg every 12 hours and kaletra (lopinavir/ritonavir) at a dose of 400 mg daily on all days of hospitalization. Yes - There is a plan to make this available What will be shared: Investigating the effect of interferon in the treatment of corona by calculating the percentage of ambient blood oxygen and the duration of hospitalization by pulse oximetry and observing the patient's clinical status and vital signs When: From the start of the project to the publication of the results To whom: Doctors active in the treatment of crona, universities of medical sciences of the country Conditions: To be used in comparison with other corona treatment methods Where to obtain: Roya rahmani How to obtain: By contacting the project manager Comments:
public Roya Rahmani
Tehranpars 198ave
Tehran Iran (Islamic Republic of) 1655753677 +98 912 465 5324 Roya.rahmani89@gmail.com Shahid Beheshti University of Medical Sciences scientific Roya Rahmani
Tehranpars 198ave
Tehran Iran (Islamic Republic of) 1655753677 +98 912 465 5324 Roya.rahmani89@gmail.com Shahid Beheshti University of Medical Sciences Iran (Islamic Republic of) Patients with Covid pneumonia who needs to hospitalised no limit no limit Both Oxygen saturation percentage above 89% B97.2 Coronavirus as the cause of disease Treatment - Drugs Treatment - Drugs "Intervention group:" people receiving recigen brand interferon beta with a dose of 12m iu eq daily for 5 days along with other common corona treatments including hydroxychloroquine 200 every 12 hours and kletra 400 (ritonavir/lopinavir) daily​ : "Control group: "Hydroxychloroquine 200 mg every 12 hours and kaletra (lopinavir/ritonavir) at a dose of 400 mg daily on all days of hospitalization Duration of hospitalization and ambient blood oxygen saturation percentage and duration of icu needed in patients who receive interferon. Timepoint: All the time spent in hospital. Method of measurement: Investigating the effect of interferon in the treatment of corona by calculating the percentage of ambient blood oxygen and the duration of hospitalization by pulse oximetry and observing the patient's clinical condition. Imam hossein hospital Approved 2023-09-04 Ethics committee of shahid beheshti University of Medical Sciences Faculty of Medicine - Shahid Beheshti University of Medical Sciences, Tehran, Quds town (West), between South Flamek and Zarafshan, Simai Iran St. - Ministry of Health, Treatment and Medical Education Central Headquarters Tehran Tehran Iran (Islamic Republic of)