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IRCT20200919048756N7 IRCT 2023-09-11 Tabriz University of Medical Sciences Comparing the effects of licorice extract gel and 0.2% chlorhexidine mouthwash on the amount of Streptococcus mutans in saliva. Comparing the effects of licorice extract gel and 0.2% chlorhexidine mouthwash on the amount of Streptococcus mutans in saliva. 2023-10-06 anticipated 60 Complete https://irct.ir/trial/72393 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Single, Purpose: Prevention, Randomization description: 60 patients are placed in two intervention and control groups using the randomization method of coin toss (tap and line) in such a way that one group is considered tap and the other group is considered line and based on the desired sample size, the same The number of coins is thrown and people are assigned to two groups, Blinding description: Mouthwash and gel will be poured into bottles. The active form of chlorhexidine mouthwash prepared for the control group is chlorhexidine hydrochloride. The evaluator of the number of Streptococcus mutans colonies in the saliva sample will not be aware of the grouping method (one-sided blind). N/A Infection or inflammation of the oral environment. Intervention 1: Intervention group: use of licorice extract mouthwash. Intervention 2: Control group: Chlorhexidine mouthwash 2%. Yes - There is a plan to make this available What will be shared: The data will be published as an article. When: After the final publication of the article resulting from the data. To whom: Public Conditions: For use in research articles and systematic reviews with citation. Where to obtain: Dr. Solmaz Maleki Dizaj, Tabriz Faculty of Dentistry How to obtain: It can be in person or by email. Comments:
public Paria Motahari
Golgasht St, Daneshgah Ave, Tabriz University of Medical Sciences, Tabriz, Iran
Tabriz Iran (Islamic Republic of) 5166614711 +98 41 3335 3161 paria.motahari@yahoo.com Tabriz University of Medical Sciences scientific Solmaz Maleki Dizaj
Golgasht
Tabriz Iran (Islamic Republic of) 5166614711 +98 41 3335 3161 maleki.s.89@gmail.com Tabriz University of Medical Sciences Iran (Islamic Republic of) Age range from 18 to 55 years good oral hygiene (using SOHI (simplified oral hygiene index) Patients willing to participate in the study 18 years 55 years Both pregnancy high blood pressure being a smoker Severe periodontal disease Patients who have taken antibiotics 2 weeks before the intervention Patients who take antibiotics during the study Patients who are allergic to licorice or it is harmful to them Prevention Prevention Intervention group: use of licorice extract mouthwash Control group: Chlorhexidine mouthwash 2% Reducing the microbial load of saliva. Timepoint: Saliva sampling will be done in two stages: one stage before starting to consume the formulations (extract and mouthwash) and the second sampling at the end of one week after consuming the formulations. Method of measurement: The prepared saliva samples are sent to the microbiology laboratory of Tabriz University of Medical Sciences to count the colonies by a microbiologist. Tabriz University of Medical Sciences Approved 2023-08-07 Ethics committee of Tabriz University of Medical Sciences Golgasht St, Daneshgah Ave, Tabriz University of Medical Sciences, Tabriz, Iran Tabriz East Azarbaijan Iran (Islamic Republic of)