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IRCT20230730058978N1 IRCT 2023-10-08 Arak University of Medical Sciences The effect of endotracheal tube cuff pressure (minimum/maximum) in the prevention of ventilator-induced pneumonia in patients admitted to ICU The effect of endotracheal tube cuff pressure (minimum/maximum) in the prevention of ventilator-induced pneumonia in patients admitted to ICU 2023-09-27 anticipated 134 Complete https://irct.ir/trial/71685 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Health service research, Randomization description: Patients will be divided into 2 groups by block randomization method (block size 4). Case sequencing is performed by an epidemiologist using an online program at www.sealedevelope.com. Hiding the random chain is done by the method of opaque envelopes, Blinding description: Due to the double-blind nature of the study, the patients and the data collector and the data analyst do not know about the groupings, but the anesthesiologist who is at the patient's bedside during surgery and knows about the grouping. N/A Ventilator-associated Pneumonia. Intervention 1: Intervention group: In a group, cuff pressure is considered as minimum normal and its amount will be 20 to 22 cm of water . Intervention 2: Intervention group: and another group The cuff pressure will be considered as maximum normal and its amount will be 30 to 32 cm of water. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Still undecided
public behnam mahmudie
valiaasr squar - valiaasr hospital
Arak Iran (Islamic Republic of) 3814957558 0098 86222202 b.mahmudie@arakmu.ac.ir Arak University of Medical Sciences scientific behnam mahmudie
valiaasr squar - valiaasr hospital
Arak Iran (Islamic Republic of) 3814957558 0098 86 222202 b.mahmudie@arakmu.ac.ir Arak University of Medical Sciences Iran (Islamic Republic of) Patients in need of mechanical ventilation, age 18 to 65 years absence of lung disease and lung mass absence of chemotherapy drugs absence of enteral nutrition absence of antibiotics before the start of VAP 18 years 65 years Both Patients who require mechanical ventilation for less than 48 hours (because they are at low risk of VAP). Lack of consent to participate in the study by the guardian Reintubation J95.851 Ventilator associated pneumonia Treatment - Devices Treatment - Devices Intervention group: In a group, cuff pressure is considered as minimum normal and its amount will be 20 to 22 cm of water . Intervention group: and another group The cuff pressure will be considered as maximum normal and its amount will be 30 to 32 cm of water. Ventilator-associated pneumonia. Timepoint: During the intervention and 4 days after the intervention. Method of measurement: Cuff Pressure Measurement. valiaasr hospital Approved 2022-12-12 Arak Medical University Sardasht - arak medical university arak Markazi Iran (Islamic Republic of)