IRCT20230709058722N1 IRCT 2024-02-04 Islamic Azad University The effect of gluten-free diet in the treatment of urticaria Comparison of the therapeutic effect of antihistamine with or without gluten-free diet in patients with urticaria 2024-02-21 anticipated 90 Complete https://irct.ir/trial/71264 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Simple random, every urticaria patient who comes to the hospital is placed in groups through a table of random numbers that have been determined in advance. Based on that, the numbers 1, 4, 7, and... in one group and the numbers 2, 3, 5, 6, 8, and 9... in the other group will be selected as random numbers, using simple random sampling method. 3 Chronic urticaria. Intervention 1: Intervention group: 90 samples of urticaria patients referred to the hospitals of this university who meet the inclusion criteria will be selected based on the random sampling method. The patients will be divided into two groups: placebo and case. Antihistamine for one month and following up the symptoms of both groups on a weekly basis using the UAS7 form, the intensity of urticaria symptoms is scored and evaluated based on the amount of itching and the number of hives. Intervention 2: Control group: A number of 90 samples of urticaria patients referred to the hospitals affiliated to this university who meet the criteria for entering the study will be selected based on the random sampling method. 100 mg daily and antihistamine for one month are investigated. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information