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IRCT20230526058299N1 IRCT 2023-07-01 Shahid Beheshti University of Medical Sciences The effect of Pamidronate Injection in the Treatment of LCP Disease Evaluation of the Effect of Monthly Intravenous Pamidronate in the Treatment of Legg Calve Perthes in Children 2023-06-22 anticipated 60 Complete https://irct.ir/trial/70485 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Among the 60 samples that meet the conditions for entering the study, people will be randomly divided into two groups, case and control, using the random block method. Using a calculator, random numbers from 1 to 60 will be generated, 30 numbers and the first number generated by the calculator will be assigned to the case group and the next 30 numbers will be assigned to the control group, Blinding description: In order to blind the statistical analyzer, a code will be assigned to the patients of each group. 3 Legg-Calve'-Perthes. Intervention 1: Intervention group: In addition to routine treatment, the group will receive pamidronate for 6 months. A 90 gram ampoule with a dose of 1 mg/kg will be injected every month. The drug will be prepared from Aburihan company and contains disodium pamidronate. Intervention 2: Control group: A group that will only receive routine treatment. Yes - There is a plan to make this available What will be shared: Demographic information and clinical trial results When: Access starts one year after results are published To whom: Researchers working in academic and scientific institutions Conditions: Research on a related issue Where to obtain: Niloofar Shashaani How to obtain: Communicating with the responsible person by email Comments:
public Niloofar Shashaani
Shariati Ave, Mofid Children's Hospital
Tehran Iran (Islamic Republic of) 1551415468 +98 21 2222 7021 shashaaniniloofar@gmail.com Shahid Beheshti University of Medical Sciences scientific Niloofar Shashaani
Shariati Ave, Mofid Children's Hospital
Tehran Iran (Islamic Republic of) 1551415468 +98 21 2222 7021 shashaaniniloofar@gmail.com Shahid Beheshti University of Medical Sciences Iran (Islamic Republic of) Patients with LCPD Consent to participate in the study no limit 18 years Both Received previous treatments receiving other similar drugs Treatment - Drugs Other Intervention group: In addition to routine treatment, the group will receive pamidronate for 6 months. A 90 gram ampoule with a dose of 1 mg/kg will be injected every month. The drug will be prepared from Aburihan company and contains disodium pamidronate. Control group: A group that will only receive routine treatment. Disease Grade. Timepoint: Referral time, six months and one year after the intervention. Method of measurement: Imaging findings and physical examination. Response to treatment. Timepoint: Referral time, six months and one year after the intervention. Method of measurement: Imaging findings and physical examination. Shahid Beheshti University of Medical Sciences Approved 2023-05-06 Ethics Committee of Shahid Beheshti University of Medical Sciences Shahid Beheshti University of Medical Sciences, Student Blvd., Valenjak, Tehran Tehran Tehran Iran (Islamic Republic of)