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IRCT20220128053844N2 IRCT 2023-05-31 Vice-Chancellor for Research and Technology, Technical and Vocational University Effect of exercise training on obese women The effect of high-intensity functional training on the expression of miR-637, CRP and lipid profile levels in overweight/obese women 2023-04-19 anticipated 24 Complete https://irct.ir/trial/70065 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Education/Guidance, Other design features: In the present study, participants were randomly assigned to two training and control groups. The control group does not receive any intervention (exercise or supplement). Blood samples are taken from the control group only in two time periods, Randomization description: Assigning samples using simple random-lottery method. In this method, first the list of names of all members is obtained. It is then assigned a number to each. It is placed inside the box. The papers are then selected and removed individually until the desired sample size is complete, Blinding description: The present study is performed in a single blind manner and the only researchers knows how to assign individuals to different groups.In general, all participants in this project are unaware of what kind of sports group they are said to be, and the researchers will individually give the exercise to individuals and will not be explained to people about the type and name of the exercise. Also, the data analyst, clinical caregiver, outcome assessor, as well as the safety committee and data monitoring will not know how to assign exercise. N/A Obesity. Intervention 1: Intervention group: Eight weeks of high-intensity interval training (HIFT). Subjects will participate in high-intensity functional training (HIFT) 3-4 days a week for 8 weeks. Blood samples are taken at rest 48 hours before the start of training and 48 hours after the last training session. The duration of the study period will be 2 months (equal to 8 weeks). Intervention 2: Control group: Control group: In this group, we will not have any exercise or drug intervention. Blood samples will be taken from the subjects in two stages (48 hours before the start of the research study and 48 hours after the last day of the research period). The duration of the study period will be 2 months (equal to 8 weeks). Yes - There is a plan to make this available What will be shared: In the meetings that will be held with the participants before and after the study, all the data and their analysis, consent and trial and study protocol will be explained to them. When: Depending on the variable, the data of some variables will be accessed before the start of the research and others after the end of the research. To whom: Project participants, researchers and university professors Conditions: Other researchers will be allowed to access the data in order to use and assist other researchers and to commit not to misuse the data. Where to obtain: Email - In-person visit How to obtain: Provide identification documents and research resume and provide commitment in order not to misuse the data Comments:
public Hamidreza zolfi
Technical and Vocational University. Manzariyeh,Tabriz,East Azerbaijan Province.
Tabriz Iran (Islamic Republic of) ۵۱۷۴۹۱۳۱۳۶ +98 41 3477 9011 Hamidreza.zolfi@yahoo.com East Azarbaijan Technical and Vocational University scientific Hamid Reza Zolfi
Technical and Vocational University of East Azarbaijan, Manzariyeh, Tabriz, East Azarbaijan
Tabriz Iran (Islamic Republic of) ۵۱۷۴۹۱۳۱۳۶ +98 41 3477 9011 hzolfi@tabrizu.ac.ir Technical and Vocational University Iran (Islamic Republic of) Age range 35 to 45 years Body mass index 25 to 35 35 years 45 years Female Smoking Taking certain medications to control body weight and blood pressure during the last three months Diastolic and systolic pressures greater than 100 and 140 mm Hg, respectively having neuromuscular diseases as well as cardio-respiratory diseases. Having cardiorespiratory diseases E66.0 Obesity due to excess calories Prevention N/A Intervention group: Eight weeks of high-intensity interval training (HIFT). Subjects will participate in high-intensity functional training (HIFT) 3-4 days a week for 8 weeks. Blood samples are taken at rest 48 hours before the start of training and 48 hours after the last training session. The duration of the study period will be 2 months (equal to 8 weeks). Control group: Control group: In this group, we will not have any exercise or drug intervention. Blood samples will be taken from the subjects in two stages (48 hours before the start of the research study and 48 hours after the last day of the research period). The duration of the study period will be 2 months (equal to 8 weeks). The level of micro RNA 637 (miR-637). Timepoint: Before and after starting eight weeks of HIFT training. Method of measurement: Real-Time PCR and using PCR mic. The level of C-Reactive Protein (CRP). Timepoint: Before and after starting eight weeks of HIFT training. Method of measurement: It will be measured by Elisa Reader method with high sensitivity. Lipid profile. Timepoint: Before and after the start of research. Method of measurement: Using the kit of Pars Azmoun company and with the sensitivity of the kit, 5 mg/dl will be measured. Technical and Vocational University Approved 2023-05-02 Ethics Committee of Research Institute of Movement Sciences KhU, No. 43. South Mofatteh Ave., Tehran. Tehran Tehran Iran (Islamic Republic of)