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IRCT20230418057953N1 IRCT 2023-05-15 Esfahan University of Medical Sciences botulinum toxin A in emotional movements of the nostrils Investigating the effect of using botulinum toxin A in emotional movements of the nostrils in patients undergone rhinoplasty. 2023-05-22 anticipated 60 Complete https://irct.ir/trial/69711 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: To generate random numbers, a table of random numbers was used, and the researcher places his finger on a number and then moves up and to the left. Based on the sample size, a number of envelopes with aluminum wrappers, prepared and each of the randomly generated sequences are written on a card and the cards are placed inside the envelopes in order. To maintain a random sequence, the outer surface of the envelopes is numbered in the same order. Finally, the lid of the envelopes is glued and placed in a box. Then, according to the order of entry of the participants in the study, an envelope is opened and a random sequence is determined. If the number inside the envelope is odd, the patient will be placed in the first group, and if it is even, the patient will be placed in the second group. 3 rhinoplasty. Intervention 1: Intervention group: injection of 100 units equivalent to 2.5 ml of botulinum toxin A manufactured in MASON pharmacological company into the muscles of the nostrils in one session after rhinoplasty. This work is done with the help of a 30 gauge needle in the Depressor septi nasi and Levator labii superior alaeque nasi muscles. the botox manufactured in MASON pharmacological company. Intervention 2: Control group: without injection. No - There is not a plan to make this available Justification or reason for not sharing IPD is no more information
public Fatemeh Mehrabipour
Hezar Jarib, Isfahan town
Isfahan Iran (Islamic Republic of) 8174673461 +98 31 3792 8134 Fatemehmehrabipour@gmail.com Esfahan University of Medical Sciences scientific Fatemeh Mehrabipour
Hezar jarib, Isfahan town
isfahan Iran (Islamic Republic of) 8174673461 +98 31 3792 8134 fatemehmehrabipour@gmail.com Esfahan University of Medical Sciences Iran (Islamic Republic of) history of rhinoplasty age between 18 and 65 informed conset 18 years 65 years Both history of psychiatric disorders using anticoagulants history of same area botox in past 6 months pregnancy and breastfeeding Z42.8 Encounter for other plastic and reconstructive surgery following medical procedure or healed injury Treatment - Drugs N/A Intervention group: injection of 100 units equivalent to 2.5 ml of botulinum toxin A manufactured in MASON pharmacological company into the muscles of the nostrils in one session after rhinoplasty. This work is done with the help of a 30 gauge needle in the Depressor septi nasi and Levator labii superior alaeque nasi muscles. the botox manufactured in MASON pharmacological company. Control group: without injection Emotional movements of nostrils. Timepoint: before the botox injection and 1 week and 1 month after injection. Method of measurement: FACE questionnaire. Esfahan University of Medical Sciences Approved 2023-04-15 Ethics committee of school of medicine of Isfahan University of Medical Sciences Isfahan, Hazar Jarib Street, Isfahan University of Medical Sciences, Building No. 3, Faculty of Medicine, Ground Floor, Department of Medical Ethics Contact number: 03137928105 Isfahan Isfehan Iran (Islamic Republic of)