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IRCT20220329054368N2 IRCT 2023-04-17 Yasouj University of Medical Sciences Investigating the effect of cyproheptadine in chronic kidney patients Investigating the effect of cyproheptadine on appetite ,laboratory and enteropometric indices in chronic renal failure pateint on hemodialysis 2023-05-21 anticipated 124 Complete https://irct.ir/trial/69566 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Supportive, Other design features: So far, the effect of cyproheptadine on appetite and laboratory parameters of chronic kidney patients has not been investigated, Randomization description: Randomization will be done in a random block method. The size of the blocks is chosen randomly (for example, blocks of 4, 8, and 12) where there is an equal number of each group in each block, Blinding description: The researcher and the participant do not know which drug is the main drug and which is the placebo. 3 Chronic kidney patients undergoing hemodialysis. Intervention 1: Intervention group: Administration of cyproheptadine 4mg daily. Intervention 2: Control group: Placebo administration. Yes - There is a plan to make this available What will be shared: Investigating the effect of cyproheptadine on appetite ,laboratory and enteropometric indices in chronic renal failure pateint on hemodialysis When: After acceptance of the article To whom: researchers Conditions: In order to expand research Where to obtain: Email to the responsible person How to obtain: Reviewing research documents of the applicant Comments:
public Farnaz sadat Javanmardi
No. 8, Eram Ave
Shiraz Iran (Islamic Republic of) 7143838466 +98 71 3229 8671 farnaz.javanmardi@yums.ac.ir Yasouj University of Medical Sciences scientific Farnaz sadat Javanmardi
No. 8, Eram Ave
Shiraz Iran (Islamic Republic of) 7143838466 +98 71 3229 8671 farnaz.javanmardi@yums.ac.ir Yasouj University of Medical Sciences Iran (Islamic Republic of) Chronic kidney patients undergoing dialysis between 18 and 80 years of age, at least three months have passed since the start of dialysis. Patients who undergo dialysis twice a week with good efficacy. People's willingness to participate in the project. Absence of accompanying disease (infection, uncompensated heart failure, malignancy, liver cirrhosis, covid-19) that causes the patient's anorexia. Not taking drugs such as tricyclic antidepressants and corticosteroids that increase appetite. 18 years 80 years Both Patient migration or death Dissatisfaction with the continuation of treatment by the patient. If other infectious or chronic diseases occur during the research period. Patients who underwent organ transplant surgery. N18.5 Chronic kidney disease, stage 5 Treatment - Drugs Placebo Intervention group: Administration of cyproheptadine 4mg daily Control group: Placebo administration Appetite. Timepoint: Before and three months after the intervention. Method of measurement: NMA questionnaire. Anthropometric indicators. Timepoint: Before and three months after the intervention. Method of measurement: Meter. Laboratory indicators. Timepoint: Before and three months after the intervention. Method of measurement: cycmax. Yasouj University of Medical Sciences Approved 2022-11-14 Ethics committee of Yasouj University of Medical Sciences Yasouj University of Medical Sciences , Shahid Motahari Blvd., Yasouj Kohgilouyeh-va-Boyrahmad Iran (Islamic Republic of)