IRCT20220604055072N2 IRCT 2023-06-28 Rashid Latif Medical College Mobilization with movement versus oscillatory mobilization Comparative effects of Mobilization with movement and oscillatory mobilization on De Quervain's tendinopathy 2023-07-20 anticipated 28 Complete https://irct.ir/trial/69530 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization is done by lottery method. In this method, each participant of the trial is assigned a unique number. In the next step these numbers are written on separate cards which are physically similar in shape, size, color etc. 35 cards were used. Then they are placed in a basket and thoroughly mixed. In the last step the slips are taken out randomly without looking at them and are placed into two sets randomly. Total of 28 cards were taken out, 14 participants in each group, Blinding description: The blinding is achieved by concealment in which the treatment allocation for each patient from the accessor. The accessor will only assess variable at pre and post intervention. This is done to avoid biasness. N/A De Quervain tendinopathy. Intervention 1: Intervention Group A: Baseline treatment of ultrasound in continuous mode with frequency of 3 MHz and intensity of 0.1 to 1.5 W/cm2 and then Manual therapy (mobilization with movement) will be performed per session. 3 sessions per week and treatment will be followed for 2 weeks . For manual therapy the patient position will be in sitting with elbow flexed and hand resting on the table. Then Mobilization with movement technique involved a lateral glide of the proximal carpal row moving on the radio-ulnar joint while the patient performed active thumb flexion. The mobilization with movement technique on carpometacarpal joint was utilized to improve abductor pollicis longus and extensor pollicis brevis soft tissue mobility. This will be repeated for 3 times per session. Intervention 2: Comparative Intervention Group B: Baseline treatment of ultrasound in continuous mode with frequency of 3 MHz and intensity of 0.1 to 1.5 W/cm2 and then Manual therapy (oscillatory Mobilization) will be performed per session. 3 sessions per week and treatment will be followed for 2 weeks For manual therapy the patient position will be in sitting with elbow flexed and hand resting on the table. Firstly Grade I and II oscillatory mobilization then III–IV posterior to anterior oscillations were performed at end range to the first carpometacarpal joint to facilitate mobility. This will be repeated for 3 times per session. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information