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IRCT20220421054606N1 IRCT 2023-05-03 Bagheiat-allah University of Medical Sciences Effect of cryotherapy (cryoablation) of posterior nasal nerve on rhinitis Evaluation of the effect of cryotherapy (cryoablation) of posterior nasal nerve on the treatment of patients with rhinitis 2023-05-22 anticipated 40 Complete https://irct.ir/trial/69342 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment. N/A Allergic or non-allergic rhinitis or a combination of both. Intervention group: In patients with rhinitis who are over 18 years old and have not responded to conventional medical treatments for at least 3 months, in the clinic environment, under local anesthesia and during nasal endoscopy, cryotherapy (cryoablation) of the posterior nasal nerve by Cryonasal device is performed for them.. Yes - There is a plan to make this available What will be shared: In this study, the data related to the main outcome (scoring of rhinitis symptoms based on the TNSS questionnaire before and after performing Cryotherapy) can be shared after de-identifying the subjects. When: The access period starts 6 months after the results are published To whom: Study data will be available only to researchers working in academic and scientific institutions Conditions: It is possible to use the data and documents to conduct additional research related to the title of the study, provided the source and the names of the researchers of this study are mentioned. Where to obtain: To receive study data and documents, they can send their request to the following email: Hossein.eshraghi313@gmail.com How to obtain: To receive study data and documents, they can send their request to the following email: Hossein.eshraghi313@gmail.com After sending an email and checking their request by the study researchers, if there is no problem, we will try to provide them with the data in a short period of time. Comments:
public Hossein Eshraghi
No. 2, Unit 16, 4th Floor, Shohadaye-Gomnam street., Shahid Mahallati Town
Tehran Iran (Islamic Republic of) 1955757608 +98 21 4022 6102 hossein.eshraghi313@gmail.com Bagheiat-allah University of Medical Sciences scientific Hossein Eshraghi
No. 2, Unit 16, 4th Floor, Shohadaye-Gomnam street., Shahid Mahallati Town
Tehran Iran (Islamic Republic of) 1955757608 +98 21 4022 6102 hossein.eshraghi313@gmail.com Bagheiat-allah University of Medical Sciences Iran (Islamic Republic of) Age above 18 years The diagnosis of rhinitis (allergic, non-allergic or a combination of both) was made by an ENT specialist based on history and examinations. Failure to respond to treatment with conventional medical drugs for at least 3 months 18 years no limit Both Patients with acute or chronic sinusitis Medicinal rhinitis (medicamentosa) Cerebrospinal fluid leakage in the form of CSF rhinorrhea Systemic diseases involving the sinonasal such as: granulomatous polyangiitis (Wegener), Sjögren's, cystic fibrosis (CF), primary ciliary movement disorder (PCD) History of frequent epistaxis, pregnancy and coagulation disorders Evidence of benign or malignant sinonasal neoplasms J30 Vasomotor and allergic rhinitis Treatment - Other Intervention group: In patients with rhinitis who are over 18 years old and have not responded to conventional medical treatments for at least 3 months, in the clinic environment, under local anesthesia and during nasal endoscopy, cryotherapy (cryoablation) of the posterior nasal nerve by Cryonasal device is performed for them. Score of rhinitis symptoms based on TNSS (Total Nasal Symptom Score) questionnaire. Timepoint: Recording the severity of rhinitis symptoms at the beginning of the study (before the start of cryotherapy) and 7 days later, one month later, three months later and six months after cryotherapy of the posterior nasal nerve. Method of measurement: TNSS (Total Nasal Symptom Score) questionnaire. Bagheiat-allah University of Medical Sciences Approved 2022-10-03 Ethics committee of Baqiyatallah University of Medical Sciences Baqiyatallah Hospital; Azam dead end alley; South Sheikh Bahai street Tehran Tehran Iran (Islamic Republic of)