IRCT20230104057046N2 IRCT 2023-03-12 Gorgan University of Medical Sciences A comparative study of the effect of mouthwashes containing tranexamic acid and nanotrangasemic acid in leukemia patients A comparative study of the effect of mouthwashes containing tranexamic acid and nanotransexamic acid for controlSpontaneous intraoral bleeding in leukemia patients: A randomized clinical trial 2023-03-16 anticipated 52 Complete https://irct.ir/trial/68923 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: We select patients from those who refer to the Desiani clinic of Golestan University of Medical Sciences according to the study entry and exit criteria. Then, based on the severity of the disease, we divide them into two groups, moderate and weak, and enter the names in a double list (in the form of a and b) in the Excel software. Then, the names are sorted separately based on random numbers for each list, and assigned to each of the drug groups one by one, Blinding description: The participants are unaware of the allocation of study groups. Bottles containing medicine are the same for both control and intervention groups. The intervention and control groups are divided into A and B, and the test participants have no knowledge of the type and group to be tested. 3 Spontaneous oral bleeding in leukemia patients. Intervention group The intervention group receives five percent nanotrangasmic acid mouthwash. Each subject will receive 4 containers of 280 ml containing mouthwash. Each patient is taught to use 20 ml mouthwash four times a day for 14 days. The participant is allowed to eat half an hour after using the mouthwash. The mouthwashes are made by pharmacists and experts in the nano field who are present as consultants in the project.. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no further information