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IRCT20230225057537N1 IRCT 2023-07-04 Mazandaran University of Medical Sciences Comparison of effect of articaine with 1:200000 epinepherine on blood glucose in diabetic and non-diabetic patients. Comparison of effect of articaine with 1:200000 epinepherine on blood glucose in type 2 diabetic and non-diabetic patients. 2023-06-26 anticipated 60 Complete https://irct.ir/trial/68830 interventional Randomization: Not randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention. 3 Effect of articaine with 1:200000 epinephrine on blood glucose in diabetic and non-diabetic patients.. Intervention 1: Intervention group: Changes of blood glucose after injection of articaine with 1:200000 epinephrine in type 2 diabetic patients. At first, in group of diabetic patients, the basic level of blood glucose concentration will be measured by a glucometer(before injection). Then, while the patient is in semi-supine position, two carpules of articaine 4% with epinephrine 1:200,000 will be injected by infiltration method. For this purpose, the needle will be inserted from the depth of the vestibule and the injection will be performed in the apex area of ​​the desired tooth root. Blood glucose levels will be measured 5 and 15 minutes after injection. Intervention 2: Intervention group: Changes of blood glucose after articaine 1:100000 epinephrine in healthy(non-diabetic) patients.At first in group of non-diabetic patients, the basic level of blood glucose concentration will be measured by a glucometer. Then, while the patient is in semi-supine position, two carpules of articaine 4% with epinephrine 1:200,000 will be injected by infiltration method. For this purpose, the needle wil be inserted from the depth of the vestibule and the injection will be performed in the apex area of ​​the desired tooth root. Blood sugar levels will be measured 5 and 15 minutes after injection. Yes - There is a plan to make this available What will be shared: Part of the data such as information of main outcome can be shared When: Access period starts 6 month after the results are published. To whom: Documents will be available only to researchers working in academic and scientific institusions. Conditions: The use of data to carry out new research projects is permitted. Where to obtain: To the email address of the respondent; Amirhosein Akbari : amirha8991@gmail.com How to obtain: After reviewing the incoming emails, the data will be send to the applicant. Comments:
public Mehdi Taghian
office unit 610. 6th floor. shriar3 building . farhang str. sari
Sari Iran (Islamic Republic of) . +98 11 3330 5443 m.taghian@mazums.ac.ir Mazandaran University of Medical Sciences scientific Mehdi Taghian
office unit 610. 6th floor. shriar3 building . farhang str. sari
Sari Iran (Islamic Republic of) . +98 11 3330 5443 m.taghian@mazums.ac.ir Mazandaran University of Medical Sciences Iran (Islamic Republic of) Patients who, according to their own report, either do not have any underlying disease or only have type 2 diabetes. Patients who need infiltration anesthesia. Patients with written consent. Patients who their diabetes is controlled. (minimum 70 mg/dl and maximum 180 mg/dl) no limit no limit Both Patients who are suffering from any other underlying disease exept type 2 diabetes. Patients who don't need infiltration anesthesia. Patients without written consent. Patients who their diabetes is not controlled. R73.0 Abnormal glucose tolerance test Treatment - Drugs Treatment - Drugs Intervention group: Changes of blood glucose after injection of articaine with 1:200000 epinephrine in type 2 diabetic patients. At first, in group of diabetic patients, the basic level of blood glucose concentration will be measured by a glucometer(before injection). Then, while the patient is in semi-supine position, two carpules of articaine 4% with epinephrine 1:200,000 will be injected by infiltration method. For this purpose, the needle will be inserted from the depth of the vestibule and the injection will be performed in the apex area of ​​the desired tooth root. Blood glucose levels will be measured 5 and 15 minutes after injection. Intervention group: Changes of blood glucose after articaine 1:100000 epinephrine in healthy(non-diabetic) patients.At first in group of non-diabetic patients, the basic level of blood glucose concentration will be measured by a glucometer. Then, while the patient is in semi-supine position, two carpules of articaine 4% with epinephrine 1:200,000 will be injected by infiltration method. For this purpose, the needle wil be inserted from the depth of the vestibule and the injection will be performed in the apex area of ​​the desired tooth root. Blood sugar levels will be measured 5 and 15 minutes after injection. Level of blood glucose. Timepoint: 1.Before injection. 2.After. 5minutes of injection 3. After15minutes of injection. Method of measurement: Blood glucose monitoring system (glucometer). Mazandaran University of Medical Sciences Approved 2023-02-16 Ethics committee of mazandaran University of Medical Sciences Mazandaran university of medical sciences. Farahabad blvd. Sari. Iran sari Mazandaran Iran (Islamic Republic of)