]>
IRCT20120524009844N10 IRCT 2023-04-13 Tabriz University of Medical Sciences Therapeutic effects and complications of hydrogen peroxide solution in genital warts Comparison of therapeutic effects and complications of 40% topical hydrogen peroxide solution with cryotherapy in genital wart lesions 2023-03-05 anticipated 40 Complete https://irct.ir/trial/68639 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: A simple randomization will be carried out on an individual basis by RandList software. The selection of patients will be based on sealed envelopes that be written A and B inside them. 40 envelopes will be prepared in two groups. After entering the clinic and before the visit, patients will receive the envelope from the secretary and hand it over to the physician. 3 Genital wart. Intervention 1: intervention group: In each patient, after examining the warts and relative matching according to the size and location, local 40% hydrogen peroxide solution will be used on one or two genital wart lesions in the intervention group. this solution will be used on the lesion to cover the entire surface of the lesion And then it will be kept for 20 seconds with rotating movements and pressure on the lesion. In each session, this cycle will be repeated 4 times, which will be 80 seconds in total. This intervention will be done at the beginning of the study and will be repeated in the third and sixth weeks if there is no improvement.For their other lesions, only standard genital wart treatment (cryotherapy) will be used.in the visit 8 weeks later, the patients will be evaluated only in terms of The effects of treatment, efficiency and side effects of receiving the drug have been checked and they will not receive intervention. Intervention 2: Control group: The Control group will be treated with liquid nitrogen cryotherapy, using spray 1-2 cm away from the lesion for 20-30 seconds, depending on the size of the wart to create a white halo around the wart as much as 1 mm. Cryotherapy (for the control group) will be performed in the first visit, the visit 3 weeks later and the visit 6 weeks later, and each time the patients will be examined in terms of the effects of the treatment, efficiency and side effects of the treatment, and in the visit 8 weeks later, the patients will be evaluated only in terms of The effects of treatment, efficiency and side effects of receiving the drug have been checked and they will not receive intervention. Yes - There is a plan to make this available What will be shared: Study data is categorized and coded with no identifiable individuals. When: Access to study data after publication of the result is available in the journal. To whom: Anyone interested in using the data can access the study data. Conditions: Study data can be used for comparison with other results. Where to obtain: Refer to the study's scientific or public accountability person for data. How to obtain: The request will be sent by email to person responsible for scientific or public inquiries. Comments:
public Dr. Mehdi Amirnia
Sina Hospital, Azadi Street, Tabriz
Tabriz Iran (Islamic Republic of) 516369888 +98 41 3549 8236 mehamir46@gmail.com Tabriz University of Medical Sciences scientific Dr. Mehdi Amirnia
Sina Hospital, Azadi Street, Tabriz
Tabriz Iran (Islamic Republic of) 516369888 +98 41 3549 8236 mehamir46@gmail.com Tabriz University of Medical Sciences Iran (Islamic Republic of) Having at least 1 genital wart Satisfaction with the study Age above 18 years 18 years no limit Both Pregnant and beast feeder women Patients who are afraid to use treatment B07.8 Other viral warts Treatment - Other Treatment - Other intervention group: In each patient, after examining the warts and relative matching according to the size and location, local 40% hydrogen peroxide solution will be used on one or two genital wart lesions in the intervention group. this solution will be used on the lesion to cover the entire surface of the lesion And then it will be kept for 20 seconds with rotating movements and pressure on the lesion. In each session, this cycle will be repeated 4 times, which will be 80 seconds in total. This intervention will be done at the beginning of the study and will be repeated in the third and sixth weeks if there is no improvement.For their other lesions, only standard genital wart treatment (cryotherapy) will be used.in the visit 8 weeks later, the patients will be evaluated only in terms of The effects of treatment, efficiency and side effects of receiving the drug have been checked and they will not receive intervention. Control group: The Control group will be treated with liquid nitrogen cryotherapy, using spray 1-2 cm away from the lesion for 20-30 seconds, depending on the size of the wart to create a white halo around the wart as much as 1 mm. Cryotherapy (for the control group) will be performed in the first visit, the visit 3 weeks later and the visit 6 weeks later, and each time the patients will be examined in terms of the effects of the treatment, efficiency and side effects of the treatment, and in the visit 8 weeks later, the patients will be evaluated only in terms of The effects of treatment, efficiency and side effects of receiving the drug have been checked and they will not receive intervention. Diameter of warts. Timepoint: Weeks 0,3,6 and 8 after treatment. Method of measurement: Clinical examination and Measure by ruler. Height of warts. Timepoint: Weeks 0,3,6 and 8 after treatment. Method of measurement: Clinical examination and measurement with caliper. Probable side effects. Timepoint: Weeks 0,3,6 and 8 after treatment. Method of measurement: Observation. Tabriz University of Medical Sciences Approved 2023-02-06 Ethics committee of Tabriz University of Medical Sciences Sina Hospital, Azadi street, Tabriz Tabriz East Azarbaijan Iran (Islamic Republic of)