IRCT20200825048515N65 IRCT 2023-02-25 Esfahan University of Medical Sciences The effect of two doses of remifentanil on bleeding rate, intraoperative hemodynamic changes, and complications after rhinoplasty surgery. Comparison of the effect of infusion of two doses of remifentanil on bleeding rate, intraoperative hemodynamic changes, and complications after rhinoplasty after general anesthesia 2023-03-06 anticipated 60 Complete https://irct.ir/trial/68496 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Before starting the study, letter A is written on 30 sheets, letter B is written on 30 sheets, and each is placed in an envelope. Then, each eligible patient who consented to participate in the study is asked to choose an envelope from among the envelopes. In this way, the patient will be randomly assigned to one of the two groups according to the envelope selected without the interference of the researcher, Blinding description: In order to achieve the triple-blind study, different doses of remifentanil will be prepared daily by the operating room nurse (without the researcher's awareness) and placed in the bag and will be labeled A and B. And is given daily to the anesthesiologist (researcher). Therefore, the patient, the Investigator, the person recording the clinical and basic information of the patients as well as the statistical analyst will not be aware of the type of intervention. 2-3 Rhinoplasty surgery candidate. Intervention 1: First intervention group: In this group, after general anesthesia, remifentanil (Exir Pharmaceutical Company) infusion is done at a rate of 50-100 micrograms/kg. Intervention 2: Second intervention group: in this group, after general anesthesia, remifentanil(Exir Pharmaceutical Company) infusion takes place at a rate of 100-150 micrograms/kg. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no further information