IRCT20120215009014N461 IRCT 2023-02-07 Hamedan University of Medical Sciences Effect of licorice mouthwash versus chlorhexidine mouthwash on oral health in intubated patients in intensive care unit Effect of licorice mouthwash versus chlorhexidine mouthwash on oral health in intubated patients in intensive care unit: a double-blind randomized clinical trial 2023-02-20 anticipated 120 Complete https://irct.ir/trial/68445 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Random assignment of the patients to the intervention and control groups through the drawing of lots. To do this, we prepare two sheets and write "intervention" on one sheet and "control" on another. Then, by referring each patient, one of the sheets will be randomly taken and the patient will be assigned to the intervention or control group, Blinding description: Patients are unconscious, therefore, the will be unaware of the type of intervention. The physician who will examine the patients will not be aware of the intervention. Thus, the trial will be run as double-blind. 3 Oral health. Intervention 1: Intervention group: Mouth washing with 15 ml of 2% licorice mouthwash solution for 30 seconds once a day for four days. Intervention 2: Control group: Mouth washing with 15 ml of 2% chlorhexidine mouthwash solution for 30 seconds once a day for four days. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is It depends on the situation and the results of the study as well as the approval of the financial supporting organization.