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IRCT20230128057259N1 IRCT 2023-02-14 Tabriz University of Medical Sciences The dental anesthetic effect of articaine compared to lidocaine Evaluation of anesthetic efficacy of incisive nerve block with articaine 4% and epinephrine 1/200000 compared to inferior alveolar nerve block with lidocaine 2% and epinephrine 1/80000 during mandibular second premolar extraction 2023-02-02 anticipated 42 Complete https://irct.ir/trial/68382 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: Random sampling will be done among the patients referred to the Faculty of Dentistry in Tabriz who are eligible for the study. The randomization method is simple and its unit is individual. Our tool for randomizing a table of random numbers. These patients will have premolars for extraction (as similar as possible) on both posterior sides of the mandible. The right side of the first referring patient will be considered as the control (lidocaine), the left side as the case (articaine), and the opposite will be done in the second patient. Patients do not know the type of intervention on each jaw side, Blinding description: This study is double-blind so the patients do not know about the type of intervention on each side of the jaw. The evaluating researcher will not know about the type of intervention performed. Patients know the type of material but do not know which side of the jaw will be used. N/A Dental problems. Intervention 1: Intervention group: Teeth will be numbed with incisive block anesthesia technique with articaine 4% along with epinephrine 1/200000 (dentacaine by Elixir company). Intervention 2: Intervention group: The tooth will be anesthetized by lower alveolar nerve block method with lidocaine 2% along with epinephrine 1/80000 (Prazocaine of Daropakhsh Company). Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information
public Mohsen Hashemi
Faculty of dentistry, Tabriz university of medical sciences, Golgasht st. Tabriz.
Tabriz Iran (Islamic Republic of) 5166614711 +98 44 3344 4598 mohsen.hashemi3263@gmail.com Tabriz University of Medical Sciences scientific Mohsen Hashemi
Faculty of dentistry, Tabriz university of medical sciences, Golgasht st. Tabriz.
Tabriz Iran (Islamic Republic of) 5166614711 +98 44 3344 4598 mohsen.hashemi3263@gmail.com Tabriz University of Medical Sciences Iran (Islamic Republic of) Consent to participate in the study Absence of systemic problem no limit no limit Both Allergy to anesthetics Pregnant or lactating women Z13.8 Encounter for screening for other specified diseases and disorders Treatment - Other Treatment - Other Intervention group: Teeth will be numbed with incisive block anesthesia technique with articaine 4% along with epinephrine 1/200000 (dentacaine by Elixir company). Intervention group: The tooth will be anesthetized by lower alveolar nerve block method with lidocaine 2% along with epinephrine 1/80000 (Prazocaine of Daropakhsh Company). Time to reach complete anesthesia. Timepoint: Immediately after the end of all injections. Method of measurement: Immediately after the end of all injections; The duration of lip numbness will be measured with the lip numbness index and by a stopwatch. The need for additional anesthesia injection. Timepoint: After starting the extraction. Method of measurement: After starting the extraction and in order to maintain complete anesthesia and painlessness of the patient during the tooth extraction, if necessary, an injection of supplementary anesthesia (pdl injection) will be performed. (Extract will not be performed until optimal anesthesia is achieved). The amount of pain. Timepoint: During tooth extraction. Method of measurement: Visual Analogue Scale. Tabriz University of Medical Sciences Approved 2022-10-03 Ethics committee of Tabriz University of Medical Sciences Research and Technology Vice-Chancellor,3rd Floor, Central Building No. 2, Tabriz University of Medical Sciences, Golgasht St., Tabriz. Tabriz East Azarbaijan Iran (Islamic Republic of)