IRCT20230123057193N1 IRCT 2023-04-17 Research assistant of Tehran University of Medical Sciences The effect of vitamin C supplementation on oxidative stress indices and skin repigmentation of patient with vitiligo The effect of vitamin C supplementation on oxidative stress indices and skin repigmentation of patient with vitiligo 2023-04-08 anticipated 44 Complete https://irct.ir/trial/68238 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: The study subjects will be block-blocked based on gender and receiving or not receiving phototherapy, and then they will be randomly divided into two intervention groups with vitamin C and placebo. Random allocation: RAS) (size 4) were assigned to intervention and placebo groups, and patients were placed in blocks of 4 based on receiving or not receiving phototherapy and gender. In this study, the participants are randomly placed in two intervention and placebo groups so that researchers can compare different treatments. Researchers and participants cannot arbitrarily play a role in assigning people to groups. Random assignment of people to the intervention or placebo group will be done by an experienced expert, Blinding description: All subjects and researchers and healthcare personnel who are responsible for the care of patients will be unaware of the existing grouping until the end of the study; In such a way, the researcher and the person who takes the sample, like the study participants, are unaware of which patient will receive the vitamin pill or the placebo. Patients are also unaware of the type of pill received. Drugs and placebos are coded by a person who is completely unaware of the study process, and this code is placed in an envelope that indicates whether it is a drug or a placebo code. One group will receive drug A and one group will receive drug B. Also, pills containing vitamin C and placebo, which have the same color, smell, and size as the vitamin pill, will be given to the study subjects every 4 weeks by another person who has no knowledge of the research process. Hence, this study will be a double-blind study. Placebo tablets contain starch and are completely similar to vitamin C tablets in terms of color, appearance and smell. Placebo tablets are also prepared by the same company that manufactures vitamin C. 2-3 Vitiligo. Intervention 1: Intervention group will receive daily 1 tablets of vitamin C 1000 mg with water for 8 weeks. Vitamin C tablets will be purchased from the Gol-darou Company with C Fix brand. All the patients will be monitored for consumption of tablets by daily checklists and recall messages. Intervention 2: The control group will receive daily 1 tablets of placebo with water for 8 weeks. placebo tablets will be purchased from the Gol-darou Company. All the patients will be monitored for consumption of tablets by daily checklists and recall messages. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Patient information will remain confidential. There is no further information.