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IRCT20221219056870N1 IRCT 2023-01-18 Dezfoul University of Medical Sciences Investigating the effect of magnesum sulfate in reducing the pain of kidney stones Comparison of the effect of intravenous ketorolac-morphine with intravenous ketorolac-magnesium sulfate on reducing pain in renal colic patients. 2023-01-07 anticipated 184 Complete https://irct.ir/trial/67877 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Other, Purpose: Treatment, Randomization description: The patients are divided into two groups, the first group receives ketorolac and morphine, and the second group receives ketorolac and magnesium sulfate. The drugs are named in uniform syringes with codes A and B and administered to the patients, Blinding description: The patients and the pain intensity scorer will be blind to the study, so that the drugs of the control and intervention groups will be prepared before the start of the intervention and will be placed in syringes of the same shape and named with A and B codes. become Medicines are prescribed to the patient by the nurse, and the researcher measures the patient's pain score according to the VAS scale at different hours, while being unaware of the type of medicine prescribed to the patient. More about this source textSource text required for additional translation information Send feedback Side panels. 2 Acute renal colic. Intervention 1: Intervention group: The acute renal colic patients of this group are prescribed magnesium sulfate with a dose of 2 grams of a 50% solution in a volume of 100cc and at a speed of 15 minutes. Intervention 2: Control group: The acute renal colic patients of this group are prescribed morphine at a dose of 0.1 mg/kg in a volume of 100 cc and at a rate of 15 minutes. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is private
public Mehdi Fallah Bagher SHeidaei
Azadegan
Dezful Iran (Islamic Republic of) 5841615797 +98 61 4242 9731 alighasemlou1374@gmail.com Dezfoul University of Medical Sciences scientific Mehdi Fallah Bagher SHeidaei
Azadegan
Dezful Iran (Islamic Republic of) 5841615797 +98 61 4242 9731 alighasemlou1374@gmail.com Dezfoul University of Medical Sciences Iran (Islamic Republic of) Patients older than 16 years Patients with flank or hypogastric pain Patients who have ultrasound based on kidney stones. 16 years no limit Both Known hypersensitivity to ketorolac and morphine or magnesium sulfate Pregnancy and breastfeeding Any history of opium addiction Breathing rate less than 12 per minute Systolic blood pressure less than 100 mm Hg Unwillingness to participate in the study Inability to understand the concept of VAS Heart or kidney failure Use of painkillers 4 hours before admission N20.0 Calculus of kidney Treatment - Drugs Treatment - Drugs Intervention group: The acute renal colic patients of this group are prescribed magnesium sulfate with a dose of 2 grams of a 50% solution in a volume of 100cc and at a speed of 15 minutes. Control group: The acute renal colic patients of this group are prescribed morphine at a dose of 0.1 mg/kg in a volume of 100 cc and at a rate of 15 minutes. Pain reduction of 3 points or more on the VAS scale after drug injection is considered positive. Timepoint: 20, 40 and 60 minutes. Method of measurement: Visual Analogue Scale. Dezfoul University of Medical Sciences Approved 2022-11-01 Ethics Committee of Dezful University of Medical Sciences azadegan Dezful Khouzestan Iran (Islamic Republic of)